1267362-25-3Relevant academic research and scientific papers
NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS
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Paragraph 0303-0304, (2020/11/03)
Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER
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Paragraph 0218-0219, (2020/12/29)
Disclosed are compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, disclosed are compounds of Formula (I) and pharmaceutical compositions thereof, and methods of using the compounds and pharmaceutical compositions in, for example, methods of treating cancer.
PRC2 INHIBITORS
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Paragraph 0203-0205, (2019/08/26)
The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))
One-pot synthesis of α,β-unsaturated esters promoted by sodium hydride
Swetha,Venkata Ramana,Shirodkar
experimental part, p. 522 - 524 (2011/12/15)
A new protocol for the synthesis of α,β-unsaturated esters was described with various aldehydes and ethyl acetate in presence of sodium hydride. Advantage of this method is high efficiency, shorter time period and inexpensive.
