126754-21-0Relevant academic research and scientific papers
Oxidation of silyl enol ethers by using IBX and IBX·N-oxide complexes: A mild and selective reaction for the synthesis of enones
Nicolaou,Gray, David L. F.,Montagnon, Tamsyn,Harrison, Scott T.
, p. 996 - 1000 (2007/10/03)
α,β-Unsaturated carbonyl compounds can be prepared by the oxidation of trimethylsilyl enol ethers with IBX (1) or IBX·MPO (2). A diverse set of carbonyl compounds can be dehydrogenated with ease by using this method. Trimethylsilyl enol ethers such as 4, which are formed in situ by the addition of an organometallic species to an enone, can be dehydrogenated with 1 or 2 to give a functionalized enone (e. g. 3 → 5). IBX = iodoxybenzoic acid; MPO = 4-methoxypyridine-N-oxide.
The vinylogous anomeric effect in 3-alkyl-2-chlorocyclohexanone oximes and oxime ethers
Denmark,Dappen,Sear,Jacobs
, p. 3466 - 3474 (2007/10/02)
A series of trans-3-alkyl-2-chlorocyclohexanones, 2(methyl, ethyl, isopropyl, and tert-butyl), have been prepared and shown to exist predominantly in the diequatorial chair conformation except the tert-butyl derivative which prefers a twist-boat. Formatio
