Technology Process of 3-(1-methylethyl)-1-(trimethylsiloxy)cyclohexene
There total 5 articles about 3-(1-methylethyl)-1-(trimethylsiloxy)cyclohexene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(CH3)2CHMgX;
With
copper(I) bromide dimethylsulfide complex;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
chloro-trimethyl-silane; cyclohexenone;
With
N,N,N,N,-tetramethylethylenediamine;
In
tetrahydrofuran;
at -78 - 25 ℃;
for 0.5h;
DOI:10.1002/1521-3773(20020315)41:6<996::AID-ANIE996>3.0.CO;2-I
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: o-iodoxybenzoic acid (IBX); 4-methoxypyridine N-oxide / dimethylsulfoxide; CH2Cl2 / 1 h / 25 °C
2.1: CuBr*SMe2 / tetrahydrofuran / 0.5 h / -78 °C
2.2: N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran / 0.5 h / -78 - 25 °C
With
4-methoxypyridine N-oxide; copper(I) bromide dimethylsulfide complex; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/1521-3773(20020315)41:6<996::AID-ANIE996>3.0.CO;2-I
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: o-iodoxybenzoic acid (IBX); 4-methoxypyridine N-oxide / dimethylsulfoxide; CH2Cl2 / 8 h / 25 °C
2.1: CuBr*SMe2 / tetrahydrofuran / 0.5 h / -78 °C
2.2: N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran / 0.5 h / -78 - 25 °C
With
4-methoxypyridine N-oxide; copper(I) bromide dimethylsulfide complex; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/1521-3773(20020315)41:6<996::AID-ANIE996>3.0.CO;2-I
