126759-62-4 Usage
Chemical structure
A derivative of indole with an acetyl group and a methoxycarbonyl group attached to the 1 and 6 positions, respectively.
Type of compound
Synthetic intermediate
Usage
Used in research and pharmaceutical development
Applications
Potential applications in the synthesis of various organic compounds and pharmaceuticals
Interest to scientists
Studied for its properties and reactivity as an indole derivative
Pharmacological activities
Investigated for potential pharmacological activities
Information source
Specific information regarding its uses and effects must be obtained from reliable and authoritative sources.
Check Digit Verification of cas no
The CAS Registry Mumber 126759-62-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,7,5 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 126759-62:
(8*1)+(7*2)+(6*6)+(5*7)+(4*5)+(3*9)+(2*6)+(1*2)=154
154 % 10 = 4
So 126759-62-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO3/c1-8(14)13-6-5-9-3-4-10(7-11(9)13)12(15)16-2/h3-7H,1-2H3
126759-62-4Relevant academic research and scientific papers
Rhodium-Catalyzed β-Selective Oxidative Heck-Type Coupling of Vinyl Acetate via C-H Activation
Zhang, Hui-Jun,Lin, Weidong,Su, Feng,Wen, Ting-Bin
supporting information, p. 6356 - 6359 (2016/12/23)
An efficient Rh(III)-catalyzed direct ortho-C-H olefination of acetanilides with vinyl acetate was developed. This protocol provides a straightforward pathway to a series of (E)-2-acetamidostyryl acetates, giving access to indole derivatives following a simple hydrolysis/cyclization process.
A Regiocontrolled Synthesis of Substituted Indoles by Palladium-Catalyzed Coupling of 2-Bromonitrobenzenes and 2-Bromoacetanilides
Kasahara, Akira,Izumi, Taeko,Murakami, Satoshi,Miyamoto, Kazuhiro,Hino, Toshimi
, p. 1405 - 1413 (2007/10/02)
The palladium-catalyzed cross-coupling reaction of 2-bromonitrobenzenes or 2-bromoacetanilides with ethylene has been used to produce a variety of substituted indoles.The mild reaction conditions and selectivity inherent in the coupling reaction have been utilized to produce regiochemically pure 4-, 5-, 6-, and 7-substituted indoles.
