126916-57-2Relevant articles and documents
Triazole antifungals. II. Synthesis and antifungal activities of 3-acyl-4-methyloxazolidine derivatives
Konosu,Tajima,Takeda,Miyaoka,Kasahara,Yasuda,Oida
, p. 2476 - 2486 (2007/10/02)
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126916-57-2
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Basic information
- Product Name: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL
- Synonyms: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL
- CAS NO:126916-57-2
- Molecular Formula: C12H14F2N4O
- Molecular Weight: 268.2625664
- EINECS: N/A
- Product Categories: N/A
- Mol File: 126916-57-2.mol
- Article Data: 1
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL(CAS DataBase Reference)
- NIST Chemistry Reference: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL(126916-57-2)
- EPA Substance Registry System: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL(126916-57-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 126916-57-2(Hazardous Substances Data)
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126916-57-2 Usage
Description
(2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL is a chiral amino alcohol derivative that features a triazole ring and a difluorophenyl group. It is classified as a triazole antifungal agent and holds promise for pharmacological applications as an antifungal drug.Used in Pharmaceutical Industry:
(2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL is used as an antifungal agent for its potential activity against various fungal pathogens. Its unique structure and functional groups make it a promising candidate for drug development and therapeutic use in treating fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 126916-57-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,9,1 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.Calculate Digit Verification of CAS Registry Number 126916-57:
(8*1)+(7*2)+(6*6)+(5*9)+(4*1)+(3*6)+(2*5)+(1*7)=142
142 % 10 = 2
So 126916-57-2 is a valid CAS Registry Number.
126916-57-2Upstream product
- 126945-34-4 Methanesulfonic acid (1S,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl ester
- 132507-89-2 (2R,3S)-2-(2,4-Difluoro-phenyl)-1-[1,2,4]triazol-1-yl-butane-2,3-diol
- 132507-89-2 threo-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
- 126918-18-1 (2S*,3R*)-2-(2,4-Difluorophenyl)-1-(dimethylisopropoxysilyl)-3-(tetrahydropyran-2-yloxy)-2-butanol
- 126918-19-2 (2S,3S)-2-(2,4-Difluoro-phenyl)-3-(tetrahydro-pyran-2-yloxy)-butane-1,2-diol
- 132563-81-6 1-(2,4-difluorophenyl)-2-(tetrahydropyranyloxy)propan-1-one
- 126918-20-5 (2R*,3R*)-2-(2,4-Difluorophenyl)-1,2,3-butanetriol
- 132507-77-8 Trifluoro-acetic acid (1R,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl ester
- 126918-21-6 (2R*,3R*)-2-(2,4-Difluorophenyl)-1,3-bis(methanesulfonyloxy)-2-butanol
- 124627-86-7 (2R*,3S*)-2-(2,4-Difluorophenyl)-3-methyl-2-<(1H-1,2,4-triazol-1-yl)methyl>oxirane
126916-57-2Downstream Products
- 126917-59-7 Furan-2-carboxylic acid [(1S,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-amide
- 126917-05-3 (E)-3-(4-Chloro-phenyl)-N-[(1S,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-acrylamide
- 126916-43-6 N-[(1S,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-4-fluoro-benzamide
- 126916-58-3 4-Chloro-N-[(1S,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-benzamide
- 126917-51-9 N-[(1S,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-3-fluoro-benzamide
- 126917-19-9 (E)-1-[(4S,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-3-(4-trifluoromethyl-phenyl)-propenone
- 132507-72-3 (4R*,5R*)-5-(2,4-Difluorophenyl)-4-methyl-3-(5-methyl-4-hexenoyl)-5-<(1H-1,2,4-triazol-1-yl)methyl>oxazolidine
- 126916-84-5 (4-Chloro-phenyl)-[(4R,5R)-5-(2,4-difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-methanone
- 126917-17-7 (E)-3-(4-Chloro-phenyl)-1-[(4S,5S)-5-(2,4-difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-propenone
- 126916-89-0 [(4R,5R)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-(4-trifluoromethyl-phenyl)-methanone
- 126945-36-6 [(4S,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-(2-fluoro-4-trifluoromethyl-phenyl)-methanone
- 126916-86-7 [(4S,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-pentafluorophenyl-methanone
- 126916-89-0 [(4S,5R)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-(4-trifluoromethyl-phenyl)-methanone
- 126916-60-7 N-[(1S,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-2,3,4,5,6-pentafluoro-benzamide
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(2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL
