126916-57-2

Basic information

• Product Name: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL
• Synonyms: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL
• CAS NO: 126916-57-2
• Molecular Formula: C₁₂H₁₄F₂N₄O
• Molecular Weight: 268.2625664
• Mol File: 126916-57-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL(126916-57-2)
• EPA Substance Registry System: (2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL(126916-57-2)

Safety Data

• Hazardous Substances Data: 126916-57-2(Hazardous Substances Data)

Usage

Description

(2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL is a chiral amino alcohol derivative that features a triazole ring and a difluorophenyl group. It is classified as a triazole antifungal agent and holds promise for pharmacological applications as an antifungal drug.
Used in Pharmaceutical Industry:
(2R,3R)-3-AMINO-2-(2,4-DIFLUORO-PHENYL)-1-[1,2,4]TRIAZOL-1-YL-BUTAN-2-OL is used as an antifungal agent for its potential activity against various fungal pathogens. Its unique structure and functional groups make it a promising candidate for drug development and therapeutic use in treating fungal infections.

Upstream product

• 126945-34-4 Methanesulfonic acid (1S,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl ester 
• 132507-89-2 (2R,3S)-2-(2,4-Difluoro-phenyl)-1-[1,2,4]triazol-1-yl-butane-2,3-diol 
• 132507-89-2 threo-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 
• 132563-81-6 1-(2,4-difluorophenyl)-2-(tetrahydropyranyloxy)propan-1-one 
• 124627-86-7 (2R^*,3S^*)-2-(2,4-Difluorophenyl)-3-methyl-2-<(1H-1,2,4-triazol-1-yl)methyl>oxirane 
• 132507-77-8 Trifluoro-acetic acid (1R,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl ester 
• 126918-21-6 (2R^*,3R^*)-2-(2,4-Difluorophenyl)-1,3-bis(methanesulfonyloxy)-2-butanol 
• 126918-18-1 (2S^*,3R^*)-2-(2,4-Difluorophenyl)-1-(dimethylisopropoxysilyl)-3-(tetrahydropyran-2-yloxy)-2-butanol 
• 126918-19-2 (2S,3S)-2-(2,4-Difluoro-phenyl)-3-(tetrahydro-pyran-2-yloxy)-butane-1,2-diol 
• 126918-20-5 (2R^*,3R^*)-2-(2,4-Difluorophenyl)-1,2,3-butanetriol 

Downstream Products

• 126917-83-7 (2R*,3R*)-3-(4-Chlorophthalimido)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol 
• 126916-43-6 N-[(1S,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-4-fluoro-benzamide 
• 126916-59-4 N-[(1S,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-4-trifluoromethyl-benzamide 
• 126917-75-7 Naphthalene-2-carboxylic acid [(1S,2S)-2-(2,4-difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-amide 
• 126917-19-9 (E)-1-[(4S,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-3-(4-trifluoromethyl-phenyl)-propenone 
• 132507-72-3 (4R^*,5R^*)-5-(2,4-Difluorophenyl)-4-methyl-3-(5-methyl-4-hexenoyl)-5-<(1H-1,2,4-triazol-1-yl)methyl>oxazolidine 
• 126916-84-5 (4-Chloro-phenyl)-[(4R,5R)-5-(2,4-difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-methanone 
• 126917-17-7 (E)-3-(4-Chloro-phenyl)-1-[(4S,5S)-5-(2,4-difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-propenone 
• 126916-89-0 [(4R,5R)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-(4-trifluoromethyl-phenyl)-methanone 
• 126945-36-6 [(4S,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-(2-fluoro-4-trifluoromethyl-phenyl)-methanone 
• 126916-86-7 [(4S,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-pentafluorophenyl-methanone 
• 126916-89-0 [(4S,5R)-5-(2,4-Difluoro-phenyl)-4-methyl-5-[1,2,4]triazol-1-ylmethyl-oxazolidin-3-yl]-(4-trifluoromethyl-phenyl)-methanone 
• 126916-45-8 1-[(4R,5S)-5-(2,4-Difluoro-phenyl)-4-methyl-oxazolidin-5-ylmethyl]-1H-[1,2,4]triazole 
• 126917-12-2 N-[(1S,2S)-2-(2,4-Difluoro-phenyl)-2-hydroxy-1-methyl-3-[1,2,4]triazol-1-yl-propyl]-2-fluoro-4-trifluoromethyl-benzamide 

Relevant articles and documents

Triazole antifungals. II. Synthesis and antifungal activities of 3-acyl-4-methyloxazolidine derivatives

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