126917-45-1 Usage
General Description
(2R,3R)-3-CHLORO-2-(2,4-DIFLUORO-PHENYL)-BUTANE-1,2-DIOL is a chemical compound with the molecular formula C10H12ClF2O2. It is a diol compound, meaning it contains two hydroxyl groups (-OH) bonded to adjacent carbon atoms. The compound also contains a chloro group and a difluoro-phenyl group, giving it its specific chemical structure. (2R,3R)-3-CHLORO-2-(2,4-DIFLUORO-PHENYL)-BUTANE-1,2-DIOL may have potential applications in pharmaceuticals, organic synthesis, or as a building block for other chemical compounds. It is important to handle this chemical with care and follow proper safety protocols due to its potential reactivity and toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 126917-45-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,9,1 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 126917-45:
(8*1)+(7*2)+(6*6)+(5*9)+(4*1)+(3*7)+(2*4)+(1*5)=141
141 % 10 = 1
So 126917-45-1 is a valid CAS Registry Number.
126917-45-1Relevant articles and documents
Concise Synthesis of Optically Active Oxirane Precursors for the Preparation of Triazole Antifungals Using the Friedel-Crafts Reaction of (S)-2-Tosyloxypropionyl Chloride
Konosu, Toshiyuki,Tajima, Yawara,Miyaoka, Takeo,Oida, Sadao
, p. 7545 - 7548 (2007/10/02)
Optically active epoxide (2R,3S)-4, a key intermediate for the preparation of triazole antifungal agents (4R,5R)-1 and (2R,3R)-2 (X = 2,4-F2), was synthesized.The Friedel-Crafts reaction between the (S)-lactic acid derivative (S)-10 and m-difluorobenzene gave the (R)-2-chloropropiophenone derivative (R)-11, which was converted into (2R,3R)-18 via Peterson olefination, stereoselective osmium(VIII) oxide oxidation, and mesylation.Treatment of (2R,3R)-18 with sodium triazolide gave (2R,3S)-4.Similarly, the 4-chlorophenyl analog (2R,3S)-4' was prepared.
