126917-45-1 Usage
Uses
Used in Pharmaceutical Industry:
(2R,3R)-3-CHLORO-2-(2,4-DIFLUORO-PHENYL)-BUTANE-1,2-DIOL is used as a potential pharmaceutical compound for its unique chemical structure and functional groups. Its diol, chloro, and difluoro-phenyl groups may contribute to its potential therapeutic properties and interactions with biological targets.
Used in Organic Synthesis:
(2R,3R)-3-CHLORO-2-(2,4-DIFLUORO-PHENYL)-BUTANE-1,2-DIOL can be used as a building block or intermediate in the synthesis of more complex organic compounds. Its specific functional groups may allow for further chemical reactions and modifications, leading to the development of new molecules with desired properties.
Used in Chemical Research:
(2R,3R)-3-CHLORO-2-(2,4-DIFLUORO-PHENYL)-BUTANE-1,2-DIOL may also be utilized in chemical research to study its reactivity, stability, and potential interactions with other compounds. Understanding its properties can contribute to the advancement of knowledge in organic chemistry and the development of new applications.
It is important to handle (2R,3R)-3-CHLORO-2-(2,4-DIFLUORO-PHENYL)-BUTANE-1,2-DIOL with care and follow proper safety protocols due to its potential reactivity and toxicity. Further research and development are necessary to fully explore its potential applications and optimize its use in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 126917-45-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,9,1 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 126917-45:
(8*1)+(7*2)+(6*6)+(5*9)+(4*1)+(3*7)+(2*4)+(1*5)=141
141 % 10 = 1
So 126917-45-1 is a valid CAS Registry Number.
126917-45-1Relevant articles and documents
Concise Synthesis of Optically Active Oxirane Precursors for the Preparation of Triazole Antifungals Using the Friedel-Crafts Reaction of (S)-2-Tosyloxypropionyl Chloride
Konosu, Toshiyuki,Tajima, Yawara,Miyaoka, Takeo,Oida, Sadao
, p. 7545 - 7548 (2007/10/02)
Optically active epoxide (2R,3S)-4, a key intermediate for the preparation of triazole antifungal agents (4R,5R)-1 and (2R,3R)-2 (X = 2,4-F2), was synthesized.The Friedel-Crafts reaction between the (S)-lactic acid derivative (S)-10 and m-difluorobenzene gave the (R)-2-chloropropiophenone derivative (R)-11, which was converted into (2R,3R)-18 via Peterson olefination, stereoselective osmium(VIII) oxide oxidation, and mesylation.Treatment of (2R,3R)-18 with sodium triazolide gave (2R,3S)-4.Similarly, the 4-chlorophenyl analog (2R,3S)-4' was prepared.
Triazole derivatives, their preparation and their use as fungicides
-
, (2008/06/13)
Compounds of formula (I): in which: Ar is optionally substituted phenyl; R1 is hydrogen or alkyl; X is optionally unsaturated alkylene, cycloalkylene or both; mis 0 or 1; -Yn-R2 is azido, phthalimido, 1-oxo-2,3-dihydro-2-isoindolyl, protected hydroxy or -OSO2R4 (in which R4 is alkyl group, haloalkyl or optionally substituted phenyl); or Y represents a group of formula -N(R5)CO-, -N(R5)CO-CH=CH-, -O-CO-, -O-CO-CH=CH-, -S-CO- or -S-CO-CH=CH- (in which R5 is hydrogen or alkyl); nis 0 or 1; R2 is alkyl, haloalkyl or optionally substituted phenyl, naphthyl or heterocyclic; and R3 is hydrogen; or R3 and -Xm-Yn-R2 together are a group of formula (II): in which R2 is as defined above, pis 0 or 1, and qis 0 or 1;, and acid addition salts thereof are fungicides, which find considerable value in the eradication of fungi in both agriculture and medicine.
