126918-27-2

Basic information

• Product Name: [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL
• Synonyms: [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL
• CAS NO: 126918-27-2
• Molecular Formula: C₁₀H₁₀F₂O₂
• Molecular Weight: 200.1820064
• Mol File: 126918-27-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL(126918-27-2)
• EPA Substance Registry System: [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL(126918-27-2)

Safety Data

• Hazardous Substances Data: 126918-27-2(Hazardous Substances Data)

Usage

Description

[(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL is a complex chiral molecule characterized by the presence of an oxiranyl group and a methanol moiety. It features a 2,4-difluoro-phenyl group attached to a 2-methyl-3-oxiranyl group, which is then connected to a methanol functional group. The specific stereochemistry of this compound is indicated by the (2R,3S) in its name, suggesting potential applications in various fields such as pharmaceuticals, agriculture, and material science. Further research is necessary to fully comprehend its properties and possible uses.

Uses

Used in Pharmaceutical Industry:
[(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL is used as a potential active pharmaceutical ingredient (API) for its unique structural features, which may offer novel therapeutic benefits in the treatment of various diseases.
Used in Agricultural Industry:
In the agricultural sector, [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL could be utilized as a component in the development of new pesticides or herbicides, leveraging its specific chemical properties to target and control pests and weeds more effectively.
Used in Material Science:
Within the field of material science, [(2R,3S)-2-(2,4-DIFLUORO-PHENYL)-3-METHYL-OXIRANYL]-METHANOL may serve as a key building block for the synthesis of advanced materials with tailored properties, such as improved mechanical strength, thermal stability, or chemical resistance.

Upstream product

• 126918-26-1 (2S,3S)-2-(2,4-Difluorophenyl)-2,3-epoxybutanal 
• 126917-43-9 (R)-(2,4-difluorophenyl) 1-chloroethyl ketone 
• 126917-44-0 (R)-3-chloro-2-(2,4-difluorophenyl)-1-butene 
• 126917-45-1 (2R,3R)-3-Chloro-2-(2,4-difluorophenyl)-1,2-butanediol 

Downstream Products

• 124627-86-7 1-(((2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)-methyl)-1H-1,2,4-triazole 

Relevant articles and documents

Concise Synthesis of Optically Active Oxirane Precursors for the Preparation of Triazole Antifungals Using the Friedel-Crafts Reaction of (S)-2-Tosyloxypropionyl Chloride

Optically active epoxide (2R,3S)-4, a key intermediate for the preparation of triazole antifungal agents (4R,5R)-1 and (2R,3R)-2 (X = 2,4-F2), was synthesized.The Friedel-Crafts reaction between the (S)-lactic acid derivative (S)-10 and m-difluorobenzene gave the (R)-2-chloropropiophenone derivative (R)-11, which was converted into (2R,3R)-18 via Peterson olefination, stereoselective osmium(VIII) oxide oxidation, and mesylation.Treatment of (2R,3R)-18 with sodium triazolide gave (2R,3S)-4.Similarly, the 4-chlorophenyl analog (2R,3S)-4' was prepared.