1269181-69-2Relevant academic research and scientific papers
Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid
Vu, Chi B.,Bemis, Jean E.,Benson, Ericka,Bista, Pradeep,Carney, David,Fahrner, Richard,Lee, Diana,Liu, Feng,Lonkar, Pallavi,Milne, Jill C.,Nichols, Andrew J.,Picarella, Dominic,Shoelson, Adam,Smith, Jesse,Ting, Amal,Wensley, Allison,Yeager, Maisy,Zimmer, Michael,Jirousek, Michael R.
supporting information, p. 1217 - 1231 (2016/02/23)
This report describes the synthesis and preliminary biological characterization of novel fatty acid niacin conjugates and fatty acid salicylate conjugates. These molecular entities were created by covalently linking two bioactive molecules, either niacin
FATTY ACID NIACIN CONJUGATES
-
Paragraph 00138, (2015/06/03)
The invention provides fatty acid niacin conjugates; pharmaceutical compositions comprising an effective amount of the fatty acid niacin conjugate; and methods for treating or preventing a metabolic disease comprising the administration of an effective amount of the fatty acid niacin conjugate.
USE OF FATTY ACID NIACIN CONJUGATES FOR TREATING DISEASES
-
Paragraph 0325, (2014/07/22)
The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate, and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate and another therapeutic agent.
METHODS OF LOWERING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9)
-
Paragraph 0237, (2014/01/07)
The invention relates to new methods of modulating cholesterol by inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9) with fatty acid derivatives; and new methods for treating or preventing a metabolic disease comprising the administration of an effective amount of a fatty acid derivative. The present invention is also directed to fatty acid bioative derivatives and their use in the treatment of metabolic diseases.
FATTY ACID NIACIN CONJUGATES AND THEIR USES
-
, (2011/04/14)
The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate.
