126933-91-3

Upstream product

• 57427-78-8 (4Z)-4-(4-methoxybenzylidene)-2-phenyl-oxazolin-5-one 
• 100-63-0 phenylhydrazine 
• 5429-22-1 4-(4-methoxybenzylidene)-2-phenyl-5(4H)-oxazolone 

Downstream Products

• 126934-07-4 3-Benzyl-8-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-1,5,6-triphenyl-5,8-dihydro-1H-[1,2,4]triazolo[3,4-f][1,2,4]triazin-8a-ol 
• 126934-03-0 5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-2,3,7-triphenyl-1,2,4-triaza-bicyclo[4.2.0]octa-3,6-dien-8-one 
• 126934-04-1 8-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-3-methyl-5,6-diphenyl-5,8-dihydro-[1,2,4]triazolo[3,4-f][1,2,4]triazine 
• 126934-00-7 5-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-2,3-diphenyl-1,2,4-triaza-bicyclo[4.2.0]octa-3,6-dien-8-one 

Relevant academic research and scientific papers

Synthesis of some new 1,2,4-Triazine and 1,2,5-Oxadiazine derivatives with antimicrobial activity

1,2,4-Triazine and 1,2,5-oxadiazine derivatives 2-12 were obtained from treated 1,3-oxazolone (1) with phenyl hydrazine or hydroxylamine hydrochloride. Chlorotriazine derivative 3 undergoing condensation reactions with different reagents produced new fused tetrazolo-triazine and triazino-quinazolinone derivatives. 1,2,5-Oxadiazine has been used as a synthon for the fused pyrazolo-oxadiazine derivative. The constitution of the prepared compounds was built up based on microanalytical and spectral data. Some of the new compounds were assessed for their antimicrobial activity.

Synthesis and reactions of imidazolinones and triazolotriazines

4-Arylidene-2-phenyl-2-imidazoline-5-thiones (2) react with alkyl halides and ethyl chloroacetate in EtONa to give alkylthioimidazoles (3).The chalcones (5) obtained from the reaction of 4-arylidene-2-phenyl-1-(p-phenacetyl)-2-imidazolin-5-ones (4) and ar