126940-11-2

Upstream product

• 38226-10-7 2-fluoro-6-hydroxybenzaldehyde 
• 107-30-2 chloromethyl methyl ether 
• 372-20-3 3-fluorophenol 
• 126940-10-1 1-fluoro-3-(methoxy-methoxy)benzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 126940-31-6 4,5-dihydro-3-(4,4-diphenylbutyl)isoxazolo<3,4,5-ef><1,4>benzoxazepine 
• 126940-26-9 3-(phenylmethyl)isoxazolo[3,4,5-ef][1,4]benzoxazepin-4(5H)-one 
• 126940-14-5 2-<<(isopropylidene)amino>oxy>-6-methoxymethoxybenzonitrile 
• 126940-13-4 2-fluoro-6-(methoxymethoxy)benzonitrile 
• 126940-15-6 3-amino-4-hydroxy-1,2-benzisoxazole 
• 126940-12-3 2-fluoro-6-methoxymethoxybenzaldehyde oxime 
• 699016-30-3 tert-butyl [(2R)-2-(3-chlorophenyl)-2-hydroxyethyl][(1R)-2-[4-[[2-formyl-3-(methoxymethoxy)-phenyl]thio]phenyl]-1-methylethyl]carbamate 

Relevant academic research and scientific papers

Regioselective formylation of 1,3-disubstituted benzenes through in situ lithiation

A facile method of regioselective formylation of disubstituted benzene via in situ deprotonation/metalation using n-BuLi/TMEDA/DIPA has been developed. Effect of different electron withdrawing and electron donating substituents in 1,3-interrelated aromatic system was studied; the metalation mostly occurred at the 2-position to afford the desired products in high yields.

Aminoalcohol derivatives

The present invention relates to a compound formula [I]: wherein R1 is hydrogen or halogen, R2 is hydrogen or an amino protective group, R3 is hydrogen or lower alkyl, X is bond, —CH2— or —O—, and Y is ?in which R4 is lower alkoxycarbonyl, ?in which R5 is carboxy(lower)alkyl, etc., ?in which R6 is hydroxy, etc., and so on, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS

The present invention relates to a compound formula [I] or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

A Novel Synthesis of 3-Amino-1,2-benzisoxazoles - an Entry into the Isoxazolobenzoxazepine Ring System

A novel synthesis of 3-amino-1,2-benzisoxazole (3) from 2-benzonitrile (2) is described.This methodology was used to synthesize 3-amino-4-hydroxy-1,2-benzisoxazole (10), which served as an intermediate for a number of isoxazolo3