126940-12-3Relevant articles and documents
A Novel Synthesis of 3-Amino-1,2-benzisoxazoles - an Entry into the Isoxazolobenzoxazepine Ring System
Shutske, Gregory M.,Kapples, Kevin J.
, p. 1293 - 1298 (2007/10/02)
A novel synthesis of 3-amino-1,2-benzisoxazole (3) from 2-benzonitrile (2) is described.This methodology was used to synthesize 3-amino-4-hydroxy-1,2-benzisoxazole (10), which served as an intermediate for a number of isoxazolo3
Necic Acid Synthons. Part 2. Regioselectivity in the Reactions of (Z)-2-Bromomethyl-2-alkenoate Esters with Selected Carbon Nucleophiles
Ameer, Farouk,Drewes, Siegfried E.,Emslie, Neville D.,Kaye, Perry T.,Mann, R. Leigh
, p. 2293 - 2295 (2007/10/02)
The preparation of selected (Z)-2-bromomethyl-2-alkenoate esters and their subsequent reaction with acetoacetic ester-derived nucleophiles is described.Both the substrate structure and the solvent system have significant effects on the regioselectivity of these nucleophilic displacements.