1269438-63-2Relevant academic research and scientific papers
Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores
D'Hooghe, Matthias,Kenis, Sara,Vervisch, Karel,Lategan, Carmen,Smith, Peter J.,Chibale, Kelly,De Kimpe, Norbert
, p. 579 - 587 (2011/03/20)
A variety of 2-(aminomethyl)aziridines was prepared and converted into the corresponding 1,2,3-triaminopropanes through a novel, microwave-assisted and regioselective ring opening by diethylamine in acetonitrile. Antiplasmodial assays revealed antimalaria
