1269755-10-3

Usage

Uses

Used in Pharmaceutical Industry:
(4-Methoxytetrahydro-2h-pyran-4-yl)MethanaMine is used as a key intermediate in the development of new drugs. Its unique structure allows for the creation of complex molecules that can be tailored for specific therapeutic applications, making it a valuable asset in medicinal chemistry.
Used in Organic Synthesis:
In the field of organic chemistry, (4-Methoxytetrahydro-2h-pyran-4-yl)MethanaMine serves as a building block for synthesizing a wide range of chemical compounds. Its presence in the structure of these compounds can influence their properties and reactivity, contributing to the advancement of organic synthesis techniques.
Used in Agrochemical Development:
(4-Methoxytetrahydro-2h-pyran-4-yl)MethanaMine is also utilized in the agrochemical industry, where it can be incorporated into the design of new pesticides, herbicides, and other agricultural chemicals. Its ability to form complex molecules makes it a promising candidate for improving the effectiveness and selectivity of these products.
Overall, (4-Methoxytetrahydro-2h-pyran-4-yl)MethanaMine has demonstrated its potential as a versatile and valuable chemical in the creation of diverse chemical compounds, with applications spanning across the pharmaceutical, organic chemistry, and agrochemical industries.

Upstream product

• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 28218-71-5 4,4-dimethoxytetrahydro-4H-pyran 
• 155650-56-9 4-cyano-4-methoxytetrahydropyran 

Downstream Products

• 1270077-00-3 6-(benzyloxy)-3-fluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine 

Relevant academic research and scientific papers

PHENYL-HETEROARYL AMINE COMPOUNDS AND THEIR USES

The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I, and pharmaceutical compositions comprising such compounds

3-(AMINOARYL)-PYRIDINE COMPOUNDS

The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are pharmaceutical compositions containing these compounds and methods of treating a disease or condition mediated by CDK9 using these compounds and compositions.

N-ACYL PYRIMIDINE BIARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a compound of the general formula (1): wherein one of X and Y is N and the other is an optionally substituted carbon atom, and Z2-Z5 represent one or two nitrogen atoms, as further described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals and as components of pharmaceutical compositions. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds described herein or pharmaceutical compositions comprising such compounds.

N-ACYL PYRIDINE BIARYL COMPOUNDS AND THEIR USES

The present invention provides a compound of general formula:wherein Z2-Z6 include one or two nitrogen atoms as described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds.

PYRIDINE BIARYL AMINE COMPOUNDS AND THEIR USES

The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds.

PYRIMIDINE BIARYL AMINE COMPOUNDS AND THEIR USES

The present invention provides a pyrimidine compound of formula (I): wherein one of X and Y but not both is N, and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tantomers, diastereomers, deuterated versions, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds

PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The present invention provides a compound of Formula (I) and pharmaceutically acceptable salts thereof. Also provided is a method of using a compound of Formula I for treating a disease or condition mediated by a CDK inhibitor.

HETEROARYL COMPOUNDS AS KINASE INHIBITORS

The present invention provides a compound of Formula (I): and pharmaceutically acceptable salts thereof. Also provided is a method of using a compound of Formula I for treating a disease or condition mediated by a CDK inhibitor

AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE

This invention relates to the provision of novel aminomethyl-substituted thiazolobenzimidazole derivatives. The novel aminomethyl-substituted thiazolobenzimidazole derivatives which have a metabotropic glutamate receptor action and excellent oral activity are invented and these derivatives are therefore useful as a medicament.