1270077-00-3

Basic information

• Product Name: 6-(benzyloxy)-3-fluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine
• Synonyms: 6-(benzyloxy)-3-fluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine
• CAS NO: 1270077-00-3
• Molecular Weight: 346.402
• Mol File: 1270077-00-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(benzyloxy)-3-fluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(benzyloxy)-3-fluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine(1270077-00-3)
• EPA Substance Registry System: 6-(benzyloxy)-3-fluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine(1270077-00-3)

Safety Data

• Hazardous Substances Data: 1270077-00-3(Hazardous Substances Data)

Upstream product

• 1270076-99-7 3,6-difluoro-N-((4-methoxytetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine 
• 100-51-6 benzyl alcohol 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 155650-56-9 4-cyano-4-methoxytetrahydropyran 
• 28218-71-5 4,4-dimethoxytetrahydro-4H-pyran 
• 1269755-10-3 (4-methoxytetrahydro-2H-pyran-4-yl)methanamine 

Relevant articles and documents

N-ACYL PYRIDINE BIARYL COMPOUNDS AND THEIR USES

The present invention provides a compound of general formula:wherein Z2-Z6 include one or two nitrogen atoms as described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds.