127-22-0

Basic information

• Product Name: taraxerol
• Synonyms: Alnulin;D-Friedoolean-14-en-3β-ol;Skimmiol;Tiliadin;Taraxero;(3β)-D-Friedoolean-14-en-3-ol;(3β13α)-13-Methyl-27-norolean-14-en-3-ol;3β-Taraxerol
• CAS NO: 127-22-0
• Molecular Formula: C30H50O
• Molecular Weight: 426.7174
• Mol File: 127-22-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 282-285°
• Boiling Point: 490.7°Cat760mmHg
• Flash Point: 217.7°C
• Appearance: /
• Density: 1.01g/cm³
• Vapor Pressure: 1.1E-11mmHg at 25°C
• Refractive Index: 1.539
• PKA: 15.19±0.70(Predicted)
• CAS DataBase Reference: taraxerol(CAS DataBase Reference)
• NIST Chemistry Reference: taraxerol(127-22-0)
• EPA Substance Registry System: taraxerol(127-22-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 127-22-0(Hazardous Substances Data)

Usage

Uses

β-Taraxerol has potential application against novel coronavirus SARS-?CoV-?2, in silico approach to assess the inhibitory potential.

Definition

ChEBI: A pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 14, with an alpha-methyl substituent at position 13 and a double bond between positions 14 and 15.

InChI:InChI=1/C30H50O/c1-25(2)17-18-27(5)13-9-21-29(7)14-10-20-26(3,4)24(31)12-16-28(20,6)22(29)11-15-30(21,8)23(27)19-25/h9,20,22-24,31H,10-19H2,1-8H3/t20?,22?,23?,24-,27-,28-,29-,30+/m0/s1

Upstream product

• 514-07-8 taraxerone 
• 2189-80-2 taraxeryl acetate 
• 514-07-8 Taraxerone 
• 141-78-6 ethyl acetate 
• 123-51-3 i-Amyl alcohol 

Downstream Products

• 2189-80-2 taraxeryl acetate 
• 514-07-8 taraxerone 
• 1679-02-3 2,9-dimethyl-picene 
• 10388-60-0 3β-benzoyloxy-D-friedo-olean-14-ene 
• 79806-73-8 taraxerol-3β-tosylate 
• 14021-23-9 taraxerol methyl ether 
• 582-16-1 2,7-dimethylnaphthalene 
• 488-23-3 1,2,3,4-Tetramethylbenzene 
• 2131-43-3 1,2,5,6-tetramethylnaphthalene 
• 486-34-0 1,2,7-trimethylnaphthalene 
• 2189-80-2 Taraxerol-acetat 
• 1269649-38-8 taraxerol 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1->3)-[2,3,4-tri-O-acetyl-α-L-rhamnopyransyl-(1->2)]-4,6-di-O-benzylidene-β-D-galactopyranoside 

Related news

taraxerol (cas 127-22-0) and Rhizophora pollen as proxies for tracking past mangrove ecosystems 1 09/28/2019

Angola Basin and Cape Basin (southeast Atlantic) surface sediments and sediment cores show that maxima in the abundance of taraxerol (relative to other land-derived lipids) covary with maxima in the relative abundance of pollen from the mangrove tree genus Rhizophora and that in the surface sedi...detailed

Research articleOptimization of methyl jasmonate and β-cyclodextrin for enhanced production of taraxerol (cas 127-22-0) and taraxasterol in (Taraxacum officinale Weber) cultures09/27/2019

ContextTaraxacum officinale Weber (TO) commonly known as “dandelion”, is a tropical Asian medicinal plant which contains taraxasterol (TX) and taraxerol (TA) in its roots, which are reported to be commercially important anticancer compounds.detailed

taraxerol (cas 127-22-0) as a possible therapeutic agent on memory impairments and Alzheimer’s disease: Effects against scopolamine and streptozotocin-induced cognitive dysfunctions09/25/2019

Alzheimer’s disease (AD) is a neurodegenerative disorder associated with cognitive impairment and cholinergic neuronal death, characteristic of the effect of time on biochemical neuronal function. The use of medicinal plants as an alternative form of prevention, or even as a possible treatment ...detailed

taraxerol (cas 127-22-0) inhibits LPS-induced inflammatory responses through suppression of TAK1 and Akt activation09/24/2019

Taraxerol, a triterpenoid compound, has potent anti-inflammatory effects. However, the molecular mechanisms are not clear. In the study, taraxerol concentration dependently inhibited nitric-oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) at the protein and mRNA levels and these inhibitions de...detailed

Relevant articles and documents

The isolation of taraxerol, taraxeryl acetate, and taraxerone from Crossostephium chinense Makino (Compositae).

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REDUCTION OF KETONES TO EPIMERIC ALCOHOLS WITH POTASSIUM HYDROXIDE-DIETHYLENE GLYCOL

Triterpenoid ketones have been reduced to epimeric alcohols on boiling with potassium hydroxide in diethylene glycol. α,β-unsaturated ketone furnished saturated epimeric alcohols.

Lithium-Ethylenediamine as a Reducing Agent

In a series of triterpenoids, ketones have been converted into sterically more stable secondary alcohols, aldehydes to primary alcohols, hindered esters to acids and isopropenyl groups to isopropyl groups on reduction with lithium in ethylenediamine in high yields.