127003-40-1

Basic information

• Product Name: 1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol
• Synonyms: 1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol;1-(2-(3-Methoxyphenethyl)phenoxy)-3-(diMethylaMino)propan-2-ol
• CAS NO: 127003-40-1
• Molecular Weight: 0
• Mol File: 127003-40-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 467.1°C at 760 mmHg
• Flash Point: 236.3°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 1.59E-09mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol(127003-40-1)
• EPA Substance Registry System: 1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol(127003-40-1)

Safety Data

• Hazardous Substances Data: 127003-40-1(Hazardous Substances Data)

Usage

General Description

1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol is a chemical compound with a long name that describes its structure. It is a phenoxy compound that contains a dimethylamino group and a 2-propanol group. The compound also contains a 3-methoxyphenyl group and an ethyl group. This chemical is often used as a pharmaceutical drug, and it may have a variety of applications including as a potential treatment for certain medical conditions. Its exact properties and potential uses would depend on further research and testing.

InChI:InChI=1/C20H27NO3/c1-21(2)14-18(22)15-24-20-10-5-4-8-17(20)12-11-16-7-6-9-19(13-16)23-3/h4-10,13,18,22H,11-12,14-15H2,1-3H3

Upstream product

• 135159-51-2 sarpogrelate hydrochloride 
• 167145-13-3 2-[2-(3-methoxyphenyl)ethyl]phenol 
• 506-59-2 N,N-dimethylammonium chloride 
• 90-02-8 salicylaldehyde 
• 33223-21-1 C₂₆H₂₄ClOP 
• 143212-74-2 1-(2-hydroxyphenyl)-2-(3-methoxyphenyl)ethylene 
• 124-40-3 dimethyl amine 

Downstream Products

• 1588890-73-6 C₂₆H₃₅NO₉ 
• 1588890-75-8 C₂₆H₃₅NO₉ 
• 135159-51-2 sarpogrelate hydrochloride 

Relevant articles and documents

Synthesis method of 2-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy)propyl-1-ol

The invention discloses a synthesis method of 2-(dimethylamino)-3-(2-(3-methoxyphenethyl)phenoxy) propyl-1-ol, and belongs to the field of organic chemical synthesis. According to the synthesis method, 2-((2-(3-methoxyphenethyl)phenoxy)methyl)ethylene oxi

Process for preparing sand Greythe ester is new hydrochloric acid

The present invention discloses a preparation method of sarpogrelate hydrochloride. According to the preparation method, 2-[2-(3-methoxyphenyl)ethyl]phenol is adopted as a starting reactant, benzyl triethylammonium chloride is adopted as a phase transfer catalyst, the starting reactant, the phase transfer catalyst and epichlorohydrin form an ether in toluene and water, dimethylamine is adopted to carry out aminolysis in a pressurization reactor after the ether is formed to obtain 1-dimethylamino-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-2-propanol, the 1-dimethylamino-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]-2-propanol and succinic anhydride are subjected to esterification in acetone, hydrogen chloride gas is directly introduced without recovery and replacement of the solvent to form a hydrochloride, and re-crystallization with acetone is performed to obtain the sarpogrelate hydrochloride refined product, wherein the purity is more than 99%.

Development of sarpogrelate external preparation for intractable pain control. I. Pre-formulation study on application of modified β-cyclodextrins

To optimize the formulation of in-hospital sarpogrelate (SPG) preparation for external use, various cyclodextrins (CDs) were investigated for their ability to improve the aqueous solubility and chemical stability of SPG. Although hydrolysis of SPG was mar