143212-74-2

Basic information

• Product Name: 2-[2-(3-Methoxyphenyl)ethenyl]phenol
• Synonyms: 2-[2-(3-Methoxyphenyl)ethenyl]phenol;2-Hydroxy-3'-methoxystilbene;2-(3-methoxystyryl)phenol
• CAS NO: 143212-74-2
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.27
• EINECS: 1312995-182-4
• Mol File: 143212-74-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 379.1 °C at 760 mmHg
• Flash Point: 212.1 °C
• Appearance: white like or light brown crystalline powder
• Density: 1.159
• CAS DataBase Reference: 2-[2-(3-Methoxyphenyl)ethenyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(3-Methoxyphenyl)ethenyl]phenol(143212-74-2)
• EPA Substance Registry System: 2-[2-(3-Methoxyphenyl)ethenyl]phenol(143212-74-2)

Safety Data

• Hazardous Substances Data: 143212-74-2(Hazardous Substances Data)

Usage

General Description

"2-[2-(3-Methoxyphenyl)ethenyl]phenol" is a complex organic compound that falls under the category of phenols, which consist of a phenyl group bonded to a hydroxyl group. This particular compound has an additional 3-methoxyphenyl group attached to it, which further contributes to its chemical properties. The presence of the methoxy group suggests that it could display stronger hydrophobic characteristics compared to other phenolic compounds. Additionally, given its specific structure, this chemical may exhibit particular reactivity or bioactivity profiles. However, specific interactions, uses, properties, or potential effects on health are not immediately clear without further research or information.

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 18880-05-2 3-methoxybenzyl-triphenylphosphonium chloride 
• 90-02-8 salicylaldehyde 
• 60815-18-1 diethyl [(3-methoxyphenyl)methyl]phosphonate 
• 874-98-6 1-bromomethyl-3-methoxybenzene 
• 5533-04-0 2-(methoxymethoxy)benzaldehyde 
• 33223-21-1 C₂₆H₂₄ClOP 

Downstream Products

• 1585206-18-3 1-[(3,4,5-trimethoxybenzyl)oxy]-2-[2-(3-methoxyphenyl)ethyl]benzene 
• 1585206-28-5 2-({2-[2-(3-methoxyphenyl)ethyl]phenoxy}methyl)thiophene 
• 1585206-27-4 5-({2-[2-(3-methoxyphenyl)ethyl]phenoxy}methyl)1,3-benzodioxole 
• 1585206-25-2 2-({2-[2-(3-methoxyphenyl)ethyl]phenoxy}methyl)pyrimidine 
• 135963-42-7 (R,S)-1-<2-<2-(3-methoxyphenyl)ethyl>phenoxy>-3-(dimethylamino)-2-propanol 
• 72279-22-2 2-(4-dimethylaminobutoxy)-3'-methoxybibenzyl 

Relevant articles and documents

A 2 - [2 - (3-methoxy-phenyl)-ethyl]-phenol synthesis method

The invention discloses a synthetic method for 2-[2-(3-methoxyphenyl)ethyl]phenol. The method comprises: firstly synthesizing diethyl 3-methoxybenzylphosphonate and 2,2-dimethoxybenzaldehyde, then successively synthesizing 1-(2,2-dimethoxyphenyl)-2-(3-methoxyphenyl)ethylene, 1-(2-phenoxy)-2-(3-methoxyphenyl)ethylene, 1-(2-acetoxphenyl)-2-(3-methoxyphenyl)ethylene and 1-(2-acetoxphenyl)-2-(3-methoxyphenyl)ethane, and finally synthesizing the product 2-[2-(3-methoxyphenyl)ethyl]phenol. The prepared 2-[2-(3-methoxyphenyl)ethyl]phenol product is good in quality and high in yield.

1-PHENYLALCOXY-2-BETA-PHENYLETHYL DERIVATIVES AS P-GLYCOPROTEIN (P-GP) INHIBITORS USEFUL IN DRUG RESISTANCE EVENTS

The invention relates to a new class of compounds, which are 1-phenylalcoxy-2-β-phenylethyl derivatives, as P-glycoprotein (P-GP) inhibitors. These compounds are useful in drug resistance events. They have been shown able to inhibit in a dose-dependent ma

Syntheses and Platelet Aggregation Inhibitory and Antithrombotic Properties of ethyl>benzenes

A series of ethyl>benzene derivatives were synthesized and evaluated for their ability to inhibit collagen-induced platelet aggregation in vitro and to protect experimantal thrombosis in mice.The results showed that the compounds were in vitro inhibitors of collagen-induced platelet aggregation.Most of them were also effective in the mouse antithrombotic assay.The compounds were found to be potent antagonists to S2 serotonergic receptor, and good correlation (r = 0.85) between their S2 serotonergic receptor antagonism and their potency as platelet antiaggregatory drugs was observed.Among the compounds studied, monophenoxy>methyl>ethyl>succinate hydrochloride (12b, MCI-9042) was selected for further pharmacological and toxicological evaluation.