127047-09-0

Basic information

• Product Name: (S)-3-Methoxycarbonyloxy-2-methyl-3-oxo-2-p-tolyl-propionic acid methyl ester
• CAS NO: 127047-09-0
• Molecular Weight: 280.277
• Mol File: 127047-09-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-Methoxycarbonyloxy-2-methyl-3-oxo-2-p-tolyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Methoxycarbonyloxy-2-methyl-3-oxo-2-p-tolyl-propionic acid methyl ester(127047-09-0)
• EPA Substance Registry System: (S)-3-Methoxycarbonyloxy-2-methyl-3-oxo-2-p-tolyl-propionic acid methyl ester(127047-09-0)

Safety Data

• Hazardous Substances Data: 127047-09-0(Hazardous Substances Data)

Upstream product

• 127047-04-5 dimethyl 2-methyl-2-(4-methylphenyl)malonate 
• 79443-97-3 methyl 2-(4-methylphenyl)propanoate 
• 877077-49-1 (R)-(+)-2-(methoxycarbonyl)-2-(4-methylphenyl)propionic acid 
• 79-22-1 methyl chloroformate 

Downstream Products

• 127047-07-8 (R)-(+)-methyl 3-hydroxy-2-methyl-2-(4-methylphenyl)propionate 
• 124990-12-1 (S)-(+)-2-methyl-2-(4-methylphenyl)butanedioic acid 
• 124909-09-7 (S)-(+)-dimethyl 2-methyl-2-(4-methylphenyl)succinate 
• 133678-86-1 (R)-(+)-4-methyl-2-oxo-4-(4-methylphenyl)-4-butanolide 
• 133678-85-0 (4R)-2-hydroxy-4-methyl-4-(4-methylphenyl)tetrahydrofuran 
• 133678-87-2 (S)-(+)-3-cyano-2-methyl-2-(4-methylphenyl)propionic acid 
• 133678-79-2 (S)-(+)-methyl 3-cyano-2-methyl-2-(4-methylphenyl)propionate 
• 133678-91-8 (S)-(+)-3-(tert-butyldimethylsiloxy)-2-methyl-2-(4-methylphenyl)propanol 
• 133678-84-9 (R)-(-)-3-(tert-butyldimethylsiloxy)-2-methyl-2-(4-methylphenyl)propanal 
• 141045-43-4 (R)-4-(tert-butyldimethylsiloxy)-3-methyl-3-(4-methylphenyl)butanal 
• 141045-42-3 (R)-4-(tert-butyldimethylsiloxy)-1-methoxy-3-methyl-3-(4-methylphenyl)but-1-ene 
• 133678-90-7 (R)-(+)-methyl 3-(tert-butyldimethylsiloxy)-2-methyl-2-(4-methylphenyl)propionate 
• 133678-88-3 (R)-(+)-methyl 2-methyl-2-(4-methylphenyl)-3-(tosyloxy)propionate 
• 133678-92-9 (2R)-(+)-2-methyl-2-(4-methylphenyl)pentane-1,4-diol 

Relevant articles and documents

Asymmetric Construction of Quaternary Carbons from Chiral Malonates: Selective and Versatile Total Syntheses of the Enantiomers of α- and β-Cuparenones from a Common Optically Active Precursor

From a single chiron (R)-4, available with high enantiomeric purity (96percent) by simple enzymatic hydrolysis (PLE) of a prochiral malonate, were prepared convenient precursors of the two enantiomers of α- and β-cuparenones (1a,b and 2a,b).This versatile

Reverse chemoselective borane reduction of an optically active malonic acid ester

Reduction of the 2-methyl-2-p-tolylmalonic monoester (+)-2 with the borane-dimethylsulfide complex took place unexpectedly on the ester function, providing the β-hydroxy-acid (-)-3. This chemoselective reaction proceeded likely through formation of a six-