127049-87-0

Basic information

• Product Name: 3-BroMo-2,6-dichloro-1-Methylbenzene
• Synonyms: 3-BroMo-2,6-dichloro-1-Methylbenzene;1-bromo-2,4-dichloro-3-methylbenzene
• CAS NO: 127049-87-0
• Molecular Formula: C₇H₅BrCl₂
• Molecular Weight: 239.9246
• EINECS: -0
• Mol File: 127049-87-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 258.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.645±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-BroMo-2,6-dichloro-1-Methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BroMo-2,6-dichloro-1-Methylbenzene(127049-87-0)
• EPA Substance Registry System: 3-BroMo-2,6-dichloro-1-Methylbenzene(127049-87-0)

Safety Data

• Hazardous Substances Data: 127049-87-0(Hazardous Substances Data)

Usage

Uses

1-Bromo-2,4-dichloro-3-methylbenzene is an intermediate used to prepare cycloalkyl lactam derivatives as 11β-HSD1 inhibitors.

Upstream product

• 118-69-4 2,6-dichlorotoluene 
• 7439-89-6 iron 

Downstream Products

• 886615-35-6 1-bromo-3-(bromomethyl)-2,4-dichlorobenzene 

Relevant articles and documents

N-SULFONYL BENZAMIDE DERIVATIVE WITH HETEROCYCLIC SUBSTITUENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF

The present invention discloses an N-sulfonyl benzamide derivative with a heterocyclic substituent, and a preparation method therefor and a pharmaceutical application thereof. More specifically, the invention discloses a compound represented by formula (II) or a pharmaceutically acceptable salt, stereoisomer, solvent compound, or prodrug thereof, and a preparation method therefor and an application thereof. Refer to the specification for definitions of each group in the formula.

Process for producing 4-benzoyl-5-hydroxypyrazoles

A process for producing a 4-benzoyl-5-hydroxylpyrazole of the formula III: STR1 which comprises reacting carbon monoxide and a 5-hydroxypyrazole of the formula II: STR2 to a substituted benzene of the formula I: STR3 wherein X is a bromine atom, an iodine atom or a diazonium tetrafluoroboron salt group, in the presence of a base and a catalyst of Group VIII of the Periodic Table.