1271330-81-4Relevant articles and documents
Efficient kinetic resolution of (±)-1,2-O-isopropylidene-3,6-di-O- benzyl-myo-inositol with the lipase B of Candida antarctica
Cunha, Aline G.,Da Silva, Angelo A.T.,Da Silva, Antonio J.R.,Tinoco, Luzineide W.,Almeida, Rodrigo V.,De Alencastro, Ricardo B.,Simas, Alessandro B.C.,Freire, Denise M.G.
, p. 2899 - 2903 (2010)
(±)-1,2-O-Isopropylidene-3,6-di-O-benzyl-myo-inositol is a relevant starting material in the synthesis of inositol phosphates and their analogs. In this study, we disclose our efforts toward an efficient methodology for the kinetic resolution of this comp
Preparation of core-shell polymer supports to immobilize lipase B from Candida antarctica: Effect of the support nature on catalytic properties
Cunha, Aline G.,Besteti, Marina D.,Manoel, Evelin A.,Da Silva, Angelo A.T.,Almeida, Rodrigo V.,Simas, Alessandro B.C.,Fernandez-Lafuente, Roberto,Pinto, Jose Carlos,Freire, Denise M.G.
, p. 59 - 67 (2014)
Core-shell supports have been prepared and utilized to immobilize lipase B from Candida antarctica. The hydrophobic nature of the supports permitted to immobilize the enzyme via interfacial activation at low ionic strength. Different supports were prepare
Kinetic resolution of (±)-1,2-O-isopropylidene-3,6-di-O-benzyl-myo- inositol by lipases: An experimental and theoretical study on the reaction of a key precursor of chiral inositols
Simas, Alessandro Bolis Costa,Silva, Angelo Amaro Theodoro Da,Cunha, Aline Gomes,Assumpcao, Rafael Silva,Hoelz, Lucas Villas Boas,Neves, Bianca Cruz,Galvao, Teca Calcagno,Almeida, Rodrigo Volcan,Albuquerque, Magaly Girao,Freire, Denise Maria Guimaraes,De Alencastro, Ricardo Bicca
experimental part, p. 32 - 40 (2012/02/03)
The study on kinetic resolution of two myo-inositol derivatives by lipases is reported. Treatment of the triether derivative, (±)-1,2-O- isopropylidene-3,5,6-tri-O-benzyl-myo-inositol, with acylating agents in the presence of different lipases did not aff