127234-85-9

Basic information

• Product Name: 2-Pyridinemethanol, 3,4-bis(phenylmethoxy)-
• CAS NO: 127234-85-9
• Molecular Formula: C20H19NO3
• Molecular Weight: 321.376
• Mol File: 127234-85-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Pyridinemethanol, 3,4-bis(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinemethanol, 3,4-bis(phenylmethoxy)-(127234-85-9)
• EPA Substance Registry System: 2-Pyridinemethanol, 3,4-bis(phenylmethoxy)-(127234-85-9)

Safety Data

• Hazardous Substances Data: 127234-85-9(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 61160-18-7 3-benzyloxy-2-methyl-1H-pyridin-4-one 
• 127234-70-2 2-methyl-3,4-di(benzyloxy)pyridine N-oxide 
• 127234-71-3 2-acetoxymethyl-3,4-di(benzyloxy)pyridine 
• 61049-69-2 3-O-benzylmaltol 
• 127234-69-9 2-methyl-3,4-di(benzyloxy)pyridine 
• 100-51-6 benzyl alcohol 
• 118-71-8 Maltol 

Downstream Products

• 862667-53-6 [3,4-bis(benzyloxy)-1-oxido-pyridin-2-yl]methanol 
• 911289-53-7 C₂₃H₂₃N₃O₄ 
• 911289-54-8 C₂₆H₂₉N₃O₄ 
• 911289-55-9 C₂₄H₂₅N₃O₄ 
• 911289-56-0 C₂₇H₃₁N₃O₄ 
• 911289-57-1 C₂₉H₂₇N₃O₄ 
• 911289-58-2 C₃₀H₂₉N₃O₄ 
• 911289-59-3 C₃₀H₂₉N₃O₄ 
• 911289-60-6 C₃₃H₃₅N₃O₄ 
• 911289-61-7 C₃₆H₃₃N₃O₄ 
• 911289-63-9 C₂₄H₂₅N₃O₄ 
• 911289-64-0 C₂₇H₂₉N₃O₄ 
• 911289-32-2 C₂₂H₂₁N₃O₄*ClH 
• 911289-31-1 C₁₉H₂₃N₃O₄*ClH 

Relevant articles and documents

Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease

A novel class of 2-amido-3-hydroxypyridin-4-one iron chelators is described. These compounds have been designed to behave as suitable molecular probes which will improve our knowledge of the role of iron in neurodegenerative conditions. Neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson disease (PD), can be considered as diverse pathological conditions sharing critical metabolic processes such as protein aggregation and oxidative stress. Interestingly, both these metabolic alterations seem to be associated with the involvement of metal ions, including iron. Iron chelation is therefore a potential therapeutic approach. The physico-chemical (pKa, pFe 3+ and log P) and biological properties (inhibition of iron-containing enzymes) of these chelators have been investigated in order to obtain a suitable profile for the treatment of neurodegenerative conditions. Studies with neuronal cell cultures confirm that the new iron chelators are neuroprotective against β-amyloid-induced toxicity.

Design and characterisation of novel hexadentate 3-hydroxypyridin-4-one ligands

Two novel hexadentate 3-hydroxypyridin-4-one ligands have been designed and synthesised. The physico-chemical properties of one of the hexadentate ligands have been determined and the results indicate that the hexadentate ligand possesses high affinity for iron(III).

3-Acylamino-1-[[[(substituted sulfonyl)amino]carbonyl]amino]2-azetidinones

Compounds having the formula and pharmaceutically acceptable salts thereof, exhibit antibacterial activity.