127264-09-9

Usage

Uses

Used in Pharmaceutical Industry:
2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethanol is used as a starting material for the synthesis of various pharmaceuticals due to its chemical reactivity and structural properties that can be further modified to create active drug compounds.
Used in Antimicrobial Applications:
In the field of antimicrobials, 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethanol is used for its potential antifungal and antibacterial properties, making it a candidate for developing new drugs to combat resistant strains of pathogens.
Used in Fragrance and Flavoring Industry:
2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethanol is used as a component in the production of fragrances and flavorings due to its aromatic properties, contributing to the creation of various scents and tastes in consumer products.
Safety Precautions:
When handling 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethanol, it is important to take proper precautions due to its potential to cause skin and eye irritation, ensuring that it is managed safely in a controlled environment.

Upstream product

• 29668-44-8 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde 
• 17253-11-1 2,3-dihydro-1,4-benzodioxin-6-ylacetic acid 
• 67200-27-5 6-vinyl-2,3-dihydrobenzo[b][1,4]dioxine 

Downstream Products

• 881656-28-6 2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl 4-methylbenzenesulfonate 
• 1021174-65-1 4-(2-bromo-5-methoxybenzyl)-1-[2-(7-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-piperidine 
• 1021174-66-2 4-(2-bromo-5-ethoxybenzyl)-1-[2-(7-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-piperidine 
• 1021174-67-3 4-[2-bromo-5-(propan-2-yloxy)benzyl]-1-[2-(7-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]piperidine 

Relevant academic research and scientific papers

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

Synthesis of Functionalized Indolines and Dihydrobenzofurans by Iron and Copper Catalyzed Aryl C-N and C-O Bond Formation

A simple and effective one-pot, two-step intramolecular aryl C-N and C-O bond forming process for the preparation of a wide range of benzo-fused heterocyclic scaffolds using iron and copper catalysis is described. Activated aryl rings were subjected to a highly regioselective, iron(III) triflimide-catalyzed iodination, followed by a copper(I)-catalyzed intramolecular N-or O-arylation step leading to indolines, dihydrobenzofurans, and six-membered analogues. The general applicability and functional group tolerance of this method were exemplified by the total synthesis of the neolignan natural product, (+)-obtusafuran. DFT calculations using Fukui functions were also performed, providing a molecular orbital rationale for the highly regioselective arene iodination process.

Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT1Aweak partial agonistic activity showing the antidepressant-like effect

We report the discovery of a novel benzylpiperidine derivative with serotonin transporter (SERT) inhibitory activity and 5-HT1Areceptor weak partial agonistic activity showing the antidepressant-like effect. The 3-methoxyphenyl group and the ph

THERAPEUTIC PROSTAGLANDIN RECEPTOR AGONISTS

Described herein are compounds which can be used in topical liquids, creams, or other dosage forms such as solids, for reducing intraocular pressure, treating glaucoma, growing hair, treating wounds, or other medical and/or cosmetic uses.

5-Quinoline derivatives having an anti-bacterial activity

The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.

PYRROLIDINE DERIVATIVES

Compounds of the formula STR1 wherein R, Y and R 1 are as defined in the specification. These compounds are muscarinic receptor antagonists which are selective for smooth muscle muscarinic sites over cardiac muscarinic sites, and are useful in the treatment of diseases associated with altered motility on tone of smooth muscle, including irritable bowel syndrome, diverticular disease, urinary incontinence, oesophageal achalasia and chronic obstructive airways disease.