127392-99-8

Basic information

• Product Name: N-[(2R)-2-benzyl-3-butenoyl]-(1S)-2,10-camphorsultam
• Synonyms: N-[(2R)-2-benzyl-3-butenoyl]-(1S)-2,10-camphorsultam
• CAS NO: 127392-99-8
• Molecular Weight: 373.516
• Mol File: 127392-99-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[(2R)-2-benzyl-3-butenoyl]-(1S)-2,10-camphorsultam(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2R)-2-benzyl-3-butenoyl]-(1S)-2,10-camphorsultam(127392-99-8)
• EPA Substance Registry System: N-[(2R)-2-benzyl-3-butenoyl]-(1S)-2,10-camphorsultam(127392-99-8)

Safety Data

• Hazardous Substances Data: 127392-99-8(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 129568-75-8 (1S)-(-)-N-but-3-enoyl-2,10-camphorsultam 
• 127392-98-7 N-(3-butenoyl)sultam 

Downstream Products

• 484051-36-7 (2R,1'R)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide 
• 484051-40-3 (3R,6R)-N-[(2,4-dimethoxyphenyl)methyl]-3,6-dibenzyl-3,6-dihydro-2-pyridone 
• 484051-51-6 (3R,6R)-3,6-dibenzyl-2-ethoxy-3,6-dihydropyridine 
• 214072-07-8 (3R,6R)-3,6-dibenzyl-3,6-dihydro-2-pyridone 
• 332424-94-9 (3R,6S)-3,6-Dibenzyl-2-ethoxy-3,6-dihydropyridine 
• 214072-06-7 (3R,6S)-3,6-dibenzyl-3,6-dihydro-1H-pyridin-2-one 
• 214072-04-5 (2R,1'S)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide 
• 214072-05-6 (3R,6S)-N-[(2,4-Dimethoxyphenyl)methyl]-3,6-dibenzyl-3,6-dihydro-2-pyridone 
• 214072-03-4 (2R)-2-benzyl-3-butenoyl chloride 
• 183509-48-0 (R)-(-)-2-benzylbut-3-enoic acid 

Relevant articles and documents

Enantioconservative synthesis and ring closing metathesis of disubstituted dialkenic amides

Optically pure disubstituted dialkenic amides 2, which are direct precursors of Z-ethylenic pseudo-peptides 1, are readily synthesized and then cyclized to lactams 3 in the presence of Grubbs' ruthenium-based metathesis catalysts with total conservation of enantiomeric purity.

ASYMMETRIC ALKYLATION OF N-ACYLSULTAMS: A GENERAL ROUTE TO ENANTIOMERICALLY PURE, CRYSTALLINE C(α,α)-DISUBSTITUTED CARBOXYLIC ACID DERIVATIVES.

Successive treatment of acylsultams 2 with nBuLi or NHMDS and primary alkyl halides, followed by crystallization, gave pure C(α)-alkylation products 4 and, via their non-destructive cleavage, enantiomerically pure alcohols 5 or carboxylic acids 6.