484051-36-7

Basic information

• Product Name: (2R,1'R)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide
• Synonyms: (2R,1'R)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide
• CAS NO: 484051-36-7
• Molecular Weight: 455.597
• Mol File: 484051-36-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,1'R)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,1'R)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide(484051-36-7)
• EPA Substance Registry System: (2R,1'R)-N-(1'-benzyl-prop-2'-enyl)-N-[(2,4-dimethoxyphenyl)methyl]-2-benzyl-but-3-enamide(484051-36-7)

Safety Data

• Hazardous Substances Data: 484051-36-7(Hazardous Substances Data)

Upstream product

• 214072-03-4 (2R)-2-benzyl-3-butenoyl chloride 
• 5267-64-1 (R)-2-amino-3-phenylpropanol 
• 673-06-3 D-(R)-phenylalanine 
• 100-39-0 benzyl bromide 
• 127392-99-8 N-[(2R)-2-benzyl-3-butenoyl]-(1S)-2,10-camphorsultam 
• 756462-76-7 (R)-1-benzyl-prop-2-enylamine 
• 440320-88-7 N-trityl-(R)-phenylalaninal 
• 183509-48-0 (R)-(-)-2-benzylbut-3-enoic acid 

Downstream Products

• 484051-40-3 (3R,6R)-N-[(2,4-dimethoxyphenyl)methyl]-3,6-dibenzyl-3,6-dihydro-2-pyridone 
• 214072-07-8 (3R,6R)-3,6-dibenzyl-3,6-dihydro-2-pyridone 
• 484051-51-6 (3R,6R)-3,6-dibenzyl-2-ethoxy-3,6-dihydropyridine 

Relevant articles and documents

An access to (Z)-ethylenic pseudodipeptides based on ring-closing metathesis

A new access to enantiopure (Z)-ethylenic pseudopeptides, starting from the chiral pool of amino acids and enantiopure 2-substituted-but-3-enoic acids is proposed and illustrated by the syntheses of the (Z)-ethylenic pseudopeptidic analogs of L-Phe-L-Phe, L-Phe-D-Phe, L-Phe-L-Val, L-Phe-D-Val and racemic (LL,DD) and (LD,DL) (phenyl)Gly-Phe. The key-steps of these syntheses are a ring-closing metathesis, catalysed by Grubbs' ruthenium alkykidene complexes, on diethylenic amides and the hydrolytic cleavage of the resulting dihydropyridones under mild conditions through intermediate formation of cyclic imidates.