127491-99-0

Upstream product

• 127492-02-8 (4R-trans)-4,6-Bis(tert-butyldimethylsiloxy)-1-cyclohexenemethanol 
• 78-39-7 Triethyl orthoacetate 
• 141803-99-8 (S)-6-Bromo-3,5-dihydroxy-hept-6-enoic acid ethyl ester 
• 127492-00-6 (4R,6S)-4,6-Dihydroxy-cyclohex-1-enecarboxylic acid methyl ester 
• 104487-42-5 (4R,6S)-4-Hydroxy-6-((S)-2-methyl-1-phenyl-propoxy)-cyclohex-1-enecarboxylic acid methyl ester 
• 127492-01-7 chiron 
• 104464-04-2 (1S,4R,8S)-8-((S)-2-Methyl-1-phenyl-propoxy)-4-(toluene-4-sulfonyl)-2-oxa-bicyclo[2.2.2]oct-5-en-3-one 
• 99268-87-8 3-(p-toluenesulfonyl)-2-pyrone 
• 141804-00-4 ethyl (3S,5S)-3,5-bis(t-butyldimethylsiloxy)-6-bromohept-6-enoate 
• 141803-98-7 (+)-ethyl (5S)-6-bromo-5-hydroxy-3-ketohept-6-enoate 
• 141803-97-6 (+)-(3S)-4-bromo-3-hydroxypent-4-enoic acid 
• 141847-49-6 (3S,5S)-3,5-bis(t-butyldimethylsiloxy)-6-bromohept-6-enal 
• 137609-91-7 (+)-ethyl (5S,7S)-5,7-bis(t-butyldimethylsiloxy)-8-bromonona-2E,8-dienoate 
• 141803-99-8 ethyl (3S,5S)-6-bromo-3,5-dihydroxyhept-6-enoate 

Downstream Products

• 161167-55-1 [(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-acetic acid ethyl ester 
• 81570-20-9 <3S-(1Z,3α,5β)>-<3,5-bis<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>acetic acid ethyl ester 
• 81506-23-2 <3S-(1E,3α,5β)>-<3,5-bis<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>acetic acid ethyl ester 

Relevant academic research and scientific papers

The Cyclization Route to the Calcitriol A-ring: A Formal Synthesis of (+)-1α,25-Dihydroxyvitamin D3

An efficient asymmetric synthesis of the A-ring of 1α,25-dihydroxyvitamin D3 from α-bromoacrolein is described.The key steps of the synthesis are the Evans type syn-selective asymmetric aldol reaction of bromoacrolein with the boron enolate of

An asymmetric synthesis of a 1α,25-dihydroxyvitamin D3 A-ring synthon

An efficient asymmetric synthesis of the A-ring of 1α,25-dihydroxyvitamin D3 from α-bromoacrolein is described. The key steps of the synthesis are the Evans type syn-selective asymmetric aldol reaction of bromoacrolein with the boron enolate of

Asymmetric total synthesis of an a-ring precursor to hormonally active 1α,25-dihydroxyvitamin D3

A new sulfinyl orthoester has been designed and used effectively in one-flask syntheses of dienoate esters from allylic alcohols; this new method as well as a highly stereocontrolled [2 + 4]-cycloaddition are applied to synthesis of 1α,25-dihydroxyvitamin D3.