127526-62-9

Upstream product

• 556-02-5 tyrosine 
• 67-56-1 methanol 
• 15924-16-0 (R)-2-amino-3-(3,5-dichloro-4-hydroxyphenyl)propanoic acid 

Downstream Products

• 127526-57-2 (R)-2-[(R)-2-(Benzyloxycarbonyl-methyl-amino)-4-methyl-pentanoylamino]-3-(3,5-dichloro-4-hydroxy-phenyl)-propionic acid 
• 173383-23-8 (S)-2-[(R)-2-((R)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-3-(3,5-dichloro-4-hydroxy-phenyl)-propionylamino]-succinamic acid 
• 173383-24-9 C₆₇H₇₁Cl₄IN₈O₁₇ 
• 173383-25-0 C₆₇H₇₀Cl₄N₈O₁₇ 
• 173383-28-3 (R)-2-((R)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-3-(3,5-dichloro-4-hydroxy-phenyl)-propionic acid 

Relevant academic research and scientific papers

Total Synthesis of Nannocystin A

Nannocystin A is a 21-membered cyclodepsipeptide showing remarkable anticancer properties. Described is the total synthesis of nannocystin A, which features an asymmetric vinylogous Mukaiyama aldol reaction for efficient assembly of the penultimate open-c