1275466-22-2Relevant academic research and scientific papers
The vinyl moiety as a handle for regiocontrol in the preparation of unsymmetrical 2,3-aliphatic-substituted indoles and pyrroles
Huestis, Malcolm P.,Chan, Lina,Stuart, David R.,Fagnou, Keith
supporting information; experimental part, p. 1338 - 1341 (2011/04/21)
Rho-Rho-Rho your boat: A rhodium catalyst effects the regioselective oxidative coupling of enynes with N-aryl ureas (X=NR2) and N-vinylacetamides (X=C(O)Me), affording the corresponding 2-alkenylindoles and 2-alkenylpyrroles in good yield. Simple hydrogenation delivers the C2/C3-aliphatic-substituted indole or pyrrole (see scheme).
