127607-72-1Relevant academic research and scientific papers
Synthesis, absolute configuration, stereoselectivity, and receptor selectivity of (αR,βS)-α,β-dimethylhistamine, a novel highly potent histamine H3 receptor agonist
Lipp,Arrang,Garbarg,Luger,Schwartz,Schunack
, p. 4434 - 4441 (2007/10/02)
Depending on the selected synthetic pathway, structural variations of the neurotransmitter histamine led to mixtures of α,β-dimethylhistamines as well as to the corresponding pure optical isomers. One of these isomers, namely (αR,βS)-α,β-dimethylhistamine
HISTAMINE DERIVATIVE, PROCESS FOR PREPARING IT AND ITS THERAPEUTIC USE
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, (2008/06/13)
The present invention relates to α,β-dimethylhistamine, of the rmula: STR1 in racemic form, or an optical isomer form or mixture of diastereoisomers and its acid addition salts. It may be prepared from an alkyl 2-amino 3-(1H-imidazol-4-yl)-carboxylate.
