76074-88-9

Basic information

• Product Name: Methyl 1-trityl-1H-iMidazole-4-carboxylate
• Synonyms: Methyl 1-trityl-1H-iMidazole-4-carboxylate
• CAS NO: 76074-88-9
• Molecular Formula: C₂₄H₂₀N₂O₂
• Molecular Weight: 368.4278
• Mol File: 76074-88-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 508.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• PKA: 2.71±0.61(Predicted)
• CAS DataBase Reference: Methyl 1-trityl-1H-iMidazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-trityl-1H-iMidazole-4-carboxylate(76074-88-9)
• EPA Substance Registry System: Methyl 1-trityl-1H-iMidazole-4-carboxylate(76074-88-9)

Safety Data

• Hazardous Substances Data: 76074-88-9(Hazardous Substances Data)

Usage

General Description

Methyl 1-trityl-1H-imidazole-4-carboxylate is a chemical compound with the molecular formula C24H20N2O2. It is a derivative of imidazole and is often used in organic synthesis and as a reagent in chemical reactions. Methyl 1-trityl-1H-iMidazole-4-carboxylate is commonly utilized in the production of pharmaceuticals, agrochemicals, and chemical research. It has various applications in the fields of medicine and science due to its unique chemical properties and versatile reactivity. Methyl 1-trityl-1H-imidazole-4-carboxylate plays a crucial role in the development and production of important chemical compounds and materials.

Upstream product

• 596-43-0 bromo-triphenyl-methane 
• 17325-26-7 Methyl imidazole-4-carboxylate 
• 76-83-5 trityl chloride 
• 17325-26-7 1H-imidazole-5-carboxylic acid methyl ester 

Downstream Products

• 127607-72-1 ethyl 3-oxo-3-<1-(triphenylmethyl)-1H-imidazol-4-yl>propanoate 
• 176721-03-2 4-<1-(2,3-dimethylphenyl)-1-hydroxyethyl>-1-(triphenylmethyl)imidazole 
• 176721-02-1 4-<(2,3-dimethylphenyl)carbonyl>-1-(triphenylmethyl)imidazole 
• 33769-07-2 4-(hydroxymethyl)-1-(triphenylmethyl)imidazole 
• 1571145-62-4 1-(1-trityl-1H-imidazol-4-yl)cyclopropanol 
• 637335-79-6 1-trityl-1H-imidazole-4-carboxylic acid (4-{[6-amino-1-butyl-3-(2-fluoro-benzyl)-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylcarbamoyl]-methyl}-phenyl)-amide 
• 191103-80-7 1H-1-triphenylmethylimidazole-4-carboxylic acid 

Relevant articles and documents

Intermediate for preparing medetomidine and its preparation method and use

The invention provides an intermediate for preparing medetomidine. The intermediate is a compound shown in the formula (I). The invention also provides a preparation method of the intermediate, and ause of the intermediate in the preparation of medetomidine. The compound shown in the formula (I) is used for preparation of medetomidine so that the raw material is cheap and easy to obtain, synthesis processes are simple, the reaction cycle is short, the environmental pollution is avoided, operation is simple, the harsh reaction conditions are avoided, the operation and post-treatment are simple, the yield and the product purity are high, the intermediate in each step is a solid and is easy to purify, a production cost is low, and the intermediate is suitable for industrial large-scale production and conforms to the principle of green chemistry.

ALDOSTERONE SYNTHASE INHIBITOR

PROBLEM TO BE SOLVED: To provide a compound having aldosterone synthase inhibition effect useful for treatment of primary aldosteronism causing hypertension or hypokalemia by overproduction of aldosterone, and a pharmaceuticals containing the compound. SOLUTION: There are provided an imidazole compound including 4-[5-(2-fluoroethyl)-1H-imidazole-1-ylmethyl]-3-iodobenzonitrile, 1-(3-bromo-4-cyanobenzyl)-1H-imidazole-5-carboxylic acid methyl, 1-(2-iodo-4-nitrobenzyl)-1H-imidazole-5-carboxylic acid methyl, 1-(3,5-di-tert-butylphenyl)-1H-imidazole-5-carboxylic acid methyl, 1-(2H-chromene-2-on-6-ylmethyl)-1H-imidazole-5-carboxylic acid methyl and 1-(2H-chromene-2-on-6-ylmethyl)-5-iodo-1H-imidazole as examples, and pharmaceuticals containing the compound. COPYRIGHT: (C)2015,JPOandINPIT

IMIDAZOLE CARBOXAMIDES

The present invention provides certain imidazole carboxamide derivatives, pharmaceutical compositions thereof, methods of using the same and processes for preparing the same.