1276113-06-4

Upstream product

• 1824-96-0 methyl ribofuranoside 
• 532-20-7 D-Ribose 
• 98-88-4 benzoyl chloride 
• 733050-13-0 methyl 3,5-di-O-(4-chlorobenzyl)-2-deoxy-2-α-(hydroxymethyl)-α-D-ribofuranoside 
• 108008-66-8 methyl 3,5-di-O-(4-chlorobenzyl)-α-D-ribofuranoside 
• 733050-11-8 methyl 3,5-di-O-(4-chlorobenzyl)-2-keto-α-D-ribofuranoside 

Downstream Products

• 1276113-07-5 methyl 3',5'-di-O-(4-chlorobenzyl)-2'-deoxy-2'-(hydroxymethyl)adenosine 
• 1276113-04-2 methyl N6-benzoyl-2'-α-(benzoyloxymethyl)-3',5'-di-O-(4-chlorobenzyl)-2'-deoxyadenosine 

Relevant academic research and scientific papers

2′-deoxy-2′-α-C-(hydroxymethyl)adenosine as potential anti-HCV agent

Because of the importance of C-branched nucleosides in the discovery of new antiviral molecules, we decided to synthesize 2′-deoxy-2′-α- C-(hydroxymethyl)adenosine as a potential anti-HCV agent. The synthesis of a new adenosine analogue following two different synthetic routes is described. The new C-branched nucleoside was tested for its antiviral activity and found to be inactive.