127665-69-4

Upstream product

• 127665-68-3 (4S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-2-penten-1-ol 
• 91751-24-5 (R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal 
• 133604-03-2 ethyl (4S)-5-(((tert-butyldiphenyl)silyl)oxy)-4-methyl-2(E)-pentenoate 
• 95514-03-7 (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 1438399-34-8 C₃₀H₄₃NO₄SSi 

Downstream Products

• 127665-70-7 tert-Butyl-[(R)-2-((2R,3S)-3-iodomethyl-oxiranyl)-propoxy]-diphenyl-silane 
• 200199-14-0 Toluene-4-sulfonic acid (2R,3R)-3-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-oxiranylmethyl ester 
• 216494-27-8 tert-Butyl-[(R)-2-((2R,3S)-3-chloromethyl-oxiranyl)-propoxy]-diphenyl-silane 
• 112763-53-8 (3S,4E,6S)-3,6-dimethyl-7-(p-tolylsulfonyloxy)-3-(tolylsulfonyloxymethyl)hepta-1,4-diene 
• 203782-80-3 Acetic acid (S)-1-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-allyl ester 
• 203782-87-0 (E)-(2S,5S)-6-(tert-Butyl-diphenyl-silanyloxy)-2,5-dimethyl-2-vinyl-hex-3-en-1-ol 
• 203782-83-6 (E)-(4S,5R)-6-(tert-Butyl-diphenyl-silanyloxy)-4-hydroxy-2,5-dimethyl-hex-2-enoic acid methyl ester 
• 203782-82-5 (E)-(4S,5R)-4-Acetoxy-6-(tert-butyl-diphenyl-silanyloxy)-2,5-dimethyl-hex-2-enoic acid methyl ester 
• 203782-84-7 (E)-(4S,5R)-6-(tert-Butyl-diphenyl-silanyloxy)-4-methanesulfonyloxy-2,5-dimethyl-hex-2-enoic acid methyl ester 
• 203782-88-1 Toluene-4-sulfonic acid (E)-(2S,5S)-6-(tert-butyl-diphenyl-silanyloxy)-2,5-dimethyl-2-vinyl-hex-3-enyl ester 
• 200199-15-1 (3S,4R)-5-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-pent-1-en-3-ol 
• 200199-16-2 (E)-(2S,5S)-6-(tert-Butyl-diphenyl-silanyloxy)-2,5-dimethyl-2-vinyl-hex-3-enoic acid methyl ester 
• 127685-45-4 (2R,3R)-4-(tert-Butyl-diphenyl-silanyloxy)-2-(2-methoxy-ethoxymethoxy)-3-methyl-butan-1-ol 
• 127665-72-9 tert-Butyl-[(2R,3R)-4-iodo-3-(2-methoxy-ethoxymethoxy)-2-methyl-butoxy]-diphenyl-silane 

Relevant academic research and scientific papers

Stereoselective synthesis of the C3-C15 fragment of callyspongiolide

The synthesis of C3-C15 fragment of callyspongiolide, a 14-membered macrolides isolated from the marine sponge Callyspongia sp., which was collected from the Indonesia, is reported. Highlights of the synthesis include construction of E-olefin through Juli

Formal synthesis of (+)-crocacin C

The formal synthesis of (+)-crocacin C is reported. The approach described takes advantage of a highly regioselective epoxide cuprate addition and a diastereoselective Overman rearrangement. The synthesis is practical and amenable to scale up.

A highly stereoselective synthesis of glycidic amides based on a new class of chiral sulfonium salts: Applications in asymmetric synthesis

A new type of chiral sulfonium salts that are characterized by a bicyclic system has been designed and synthesized from α-amino acids. Their corresponding ylides, which were prepared by basic treatment of the sulfonium salts, reacted smoothly with a broad array of simple and chiral aldehydes to provide trans-epoxy amides in reasonable to very good yields and excellent stereoselectivities (>98 %). The obtained epoxy amides were found to be useful as synthetic building blocks. Thus, they were reduced into their corresponding epoxy alcohols and subjected to oxirane-ring-opening reactions with different types of nucleophiles.