127665-69-4

Upstream product

• 127665-68-3 (4S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-2-penten-1-ol 
• 91751-24-5 (R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal 
• 133604-03-2 ethyl (4S)-5-(((tert-butyldiphenyl)silyl)oxy)-4-methyl-2(E)-pentenoate 
• 95514-03-7 (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 1438399-34-8 C₃₀H₄₃NO₄SSi 

Downstream Products

• 200199-14-0 Toluene-4-sulfonic acid (2R,3R)-3-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-oxiranylmethyl ester 
• 216494-27-8 tert-Butyl-[(R)-2-((2R,3S)-3-chloromethyl-oxiranyl)-propoxy]-diphenyl-silane 
• 1369677-28-0 C₂₃H₃₄O₃Si 
• 124887-13-4 (2S,3S,4R)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentane-1,3-diol 
• 1369677-32-6 (2R,3R,4S)-5-(benzyloxy)-3-methoxy-2,4-dimethylpentan-1-ol 
• 176444-25-0 C₁₅H₂₂O₃ 
• 1369677-36-0 C₂₃H₂₈O₃ 
• 1369677-52-0 C₂₃H₃₀O₃ 
• 1369677-38-2 C₂₃H₃₀O₃ 
• 1369677-40-6 C₂₅H₃₂O₄ 
• 127665-75-2 2-[(2S,3R)-4-(tert-Butyl-diphenyl-silanyloxy)-2-(2-methoxy-ethoxymethoxy)-3-methyl-butyl]-2-[(E)-(R)-1-(2-trimethylsilanyl-ethoxymethoxy)-but-2-enyl]-[1,3]dithiane 
• 127758-11-6 2-[(2S,3R)-4-(tert-Butyl-diphenyl-silanyloxy)-2-(2-methoxy-ethoxymethoxy)-3-methyl-butyl]-2-[(E)-(S)-1-(2-trimethylsilanyl-ethoxymethoxy)-but-2-enyl]-[1,3]dithiane 
• 127665-74-1 (E)-1-{2-[(2S,3R)-4-(tert-Butyl-diphenyl-silanyloxy)-2-(2-methoxy-ethoxymethoxy)-3-methyl-butyl]-[1,3]dithian-2-yl}-but-2-en-1-ol 
• 127665-71-8 tert-Butyl-[(2R,3S)-3-(2-methoxy-ethoxymethoxy)-2-methyl-pent-4-enyloxy]-diphenyl-silane 

Relevant academic research and scientific papers

Stereoselective synthesis of the C3-C15 fragment of callyspongiolide

The synthesis of C3-C15 fragment of callyspongiolide, a 14-membered macrolides isolated from the marine sponge Callyspongia sp., which was collected from the Indonesia, is reported. Highlights of the synthesis include construction of E-olefin through Juli

A highly stereoselective synthesis of glycidic amides based on a new class of chiral sulfonium salts: Applications in asymmetric synthesis

A new type of chiral sulfonium salts that are characterized by a bicyclic system has been designed and synthesized from α-amino acids. Their corresponding ylides, which were prepared by basic treatment of the sulfonium salts, reacted smoothly with a broad array of simple and chiral aldehydes to provide trans-epoxy amides in reasonable to very good yields and excellent stereoselectivities (>98 %). The obtained epoxy amides were found to be useful as synthetic building blocks. Thus, they were reduced into their corresponding epoxy alcohols and subjected to oxirane-ring-opening reactions with different types of nucleophiles.

Formal synthesis of (+)-crocacin C

The formal synthesis of (+)-crocacin C is reported. The approach described takes advantage of a highly regioselective epoxide cuprate addition and a diastereoselective Overman rearrangement. The synthesis is practical and amenable to scale up.