124887-13-4

Upstream product

• 132950-29-9 (2S,3S,4R)-1-(benzyloxy)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentan-3-ol 
• 132950-30-2 (2S,4R)-1-(benzyloxy)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentan-3-one 
• 917-54-4 methyllithium 
• 127665-69-4 ((2R,3R)-3-((R)-1-((tert-butyldiphenylsilyl)oxy)propan-2-yl)oxiran-2-yl)methanol 
• 127665-68-3 (4S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-2-penten-1-ol 
• 91751-24-5 (R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropanal 
• 133604-03-2 ethyl (4S)-5-(((tert-butyldiphenyl)silyl)oxy)-4-methyl-2(E)-pentenoate 
• 95514-03-7 (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 209250-90-8 (2R,3R,4R)-5-(tert-Butyl-diphenyl-silanyloxy)-3-hydroxy-2,4-dimethyl-pentanal 
• 89395-27-7 (3R,4S,5R)-4-hydroxy-3,5-dimethyl-tetrahydro-(2H)-pyran-2-one 
• 123284-89-9 (+/-)-2-methyl-3-[(tert-butyldiphenylsilyl)oxy]propanal 
• 89329-05-5 1-methyl hydrogen (3S,2R,4S)-3-hydroxy-2,4-dimethylglutarate 
• 105365-06-8 methyl 3,5-dihydoxy-2,4-dimethylpentanoate 

Downstream Products

• 124887-14-5 (2R,3S,4S)-1-<(tert-butyl)diphenylsilyloxy>-3,5-(isopropylidenedioxy)-2,4-dimethylpentane 
• 132950-29-9 (2S,3S,4R)-1-(benzyloxy)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentan-3-ol 
• 1369677-32-6 (2R,3R,4S)-5-(benzyloxy)-3-methoxy-2,4-dimethylpentan-1-ol 
• 176444-25-0 C₁₅H₂₂O₃ 
• 1369677-36-0 C₂₃H₂₈O₃ 
• 1369677-52-0 C₂₃H₃₀O₃ 
• 1369677-38-2 C₂₃H₃₀O₃ 
• 1369677-40-6 C₂₅H₃₂O₄ 
• 329362-90-5 (2R,3R,4R,5S,E)-3,5-dimethoxy-2,4-dimethyl-7-phenylhept-6-enal 
• 307492-71-3 3,5-dimethoxy-2,4-dimethyl-7-phenyl-(2S,3S,4R,5S,6E)-6-hepten-1-ol 
• 329362-97-2 ethyl 7,9-dimethoxy-3,6,8-trimethyl-11-phenyl-(2E,4E,6S,7S,8R,9S,10E)-2,4,10-undecatrienoate 
• 135681-55-9 2',6'-dimethylphenyl (2R,3R,4R,5R,6S)-3-hydroxy-5,7-isopropylidenedioxy-2,4,6-trimethylheptanonate 

Relevant academic research and scientific papers

Stereoselective synthesis of a building block corresponding to the C(1)-to-C(7) moiety of 14-membered macrolide antibiotics

The synthesis of 2',6'-dimethylphenyl (2R,3R,4R,5R,6S)-3-hydroxy-5,7-isopropylidenedioxy-2,4,6-trimethylhepta noate (13) a synthon for the C(1)-to-C(7) segment of a number of 14-membered macrolide antibiotics is described, starting from the meso-diester 3

Enantioselective synthesis of anti - And syn -homopropargyl alcohols via chiral Br?nsted acid catalyzed asymmetric allenylboration reactions

Chiral Br?nsted acid catalyzed asymmetric allenylboration reactions are described. Under optimized conditions, anti-homopropargyl alcohols 2 are obtained in high yields with excellent diastereo- and enantioselectivities from stereochemically matched aldeh

Formal synthesis of (+)-crocacin C

The formal synthesis of (+)-crocacin C is reported. The approach described takes advantage of a highly regioselective epoxide cuprate addition and a diastereoselective Overman rearrangement. The synthesis is practical and amenable to scale up.

Diastereoselective Mukaiyama and free radical processes for the synthesis of polypropionate units

(Matrix Presented) Reported herein is the synthesis of 8 out of 16 polypropionates derived from our propionate units. A new strategy involving a stereoselective Mukaiyama aldol reaction followed by a stereoselective free-radical-based hydrogen transfer, b

SYNTHESIS OF A VERSATILE CHIRAL SYNTHON CORRESPONDING TO THE C(1) to C(7) SEGMENT OF 14-MEMBERED MACROLIDE ANTIBIOTICS

The synthesis of the C(1) to C(7) segment of a number of 14-membered macrolide antibiotics is described, starting from dimethyl 3-hydroxy-2,4-dimethylglutarate.

STEREOCHEMICAL CONSEQUENCES FOR THE LEWIS ACID MEDIATED ADDITIONS OF ALLYL AND CROTYLTRI-n-BUTYLSTANNANE TO CHIRAL β-HYDROXYALDEHYDE DERIVATIVES

Proper choice of Lewis acid and hydroxyl protecting group allows for selective addition of crotyltri-n-butylstannane to either face of the aldehyde carbonyl in derivatives of 2-methyl-3-hydroxypropanal with preservation of erythro selectivity for the bond