1276666-10-4

Basic information

• Product Name: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate
• Synonyms: [2-[(5-Chloro-benzooxazol-2-yl)(3-oxobutyl)amino]ethyl]carbamic acid tert-butyl ester;tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate;Carbamic acid, N-[2-[(5-chloro-2-benzoxazolyl)(3-oxobutyl)amino]ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 1276666-10-4
• Molecular Formula: C₁₈H₂₄ClN₃O₄
• Molecular Weight: 381.85386
• Mol File: 1276666-10-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 145-148℃
• Appearance: /
• CAS DataBase Reference: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate(1276666-10-4)
• EPA Substance Registry System: tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)aMino)ethylcarbaMate(1276666-10-4)

Safety Data

• Hazardous Substances Data: 1276666-10-4(Hazardous Substances Data)

Usage

Description

Tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is a complex organic compound that features a tert-butyl functional group, a 5-chlorobenzo[d]oxazol-2-yl group, and a 3-oxobutylamino group. It is an ethylcarbamate derivative, characterized by the presence of a carbamate functional group. tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is utilized in various chemical and pharmaceutical applications, primarily as an intermediate in the synthesis of other compounds and as a potential pharmacological agent. Its specific properties and applications are contingent upon its precise chemical composition and structure, necessitating further research to explore its full potential.

Uses

Used in Chemical Synthesis:
Tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is used as an intermediate in chemical synthesis for the production of other complex organic compounds. Its unique molecular structure allows it to serve as a building block in the creation of various chemical entities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is used as a potential pharmacological agent. Its specific molecular features may contribute to the development of new drugs, particularly in the areas of medicinal chemistry where novel compounds are constantly being explored for therapeutic applications.
Used in Research and Development:
Tert-butyl 2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethylcarbamate is also utilized in research and development settings to study its chemical properties and explore its potential uses in various fields. This includes understanding its reactivity, stability, and how it can be modified or combined with other compounds to create new materials or drugs.

Upstream product

• 22876-19-3 5-chloro-2-mercaptobenzoxazole 
• 57260-73-8 N-BOC-1,2-diaminoethane 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 1276666-16-0 C₁₃H₁₆ClN₃O*C₁₈H₁₄O₈ 
• 1276666-14-8 C₁₃H₁₆ClN₃O*C₁₈H₁₄O₈ 
• 1030377-33-3 Suvorexant 

Relevant articles and documents

A [2 - [(5 - chloro - benzo oxazole - 2 - yl) (3 - oxo-butyl) amino] ethyl] carbamic acid tert-butyl preparation method (by machine translation)

The invention discloses a [2 - [(5 - chloro - benzo oxazole - 2 - yl) (3 - oxo-butyl) amino] ethyl] carbamic acid tert-butyl preparation method, in order to ethylenediamine, vinyl, 2 - amino - 4 - chlorophenol and the like as raw materials, after five-step reaction to obtain the target product [2 - [(5 - chloro - benzo oxazole - 2 - yl) (3 - oxo-butyl) amino] ethyl] tert-butyl carbamate. The invention has simple operation, environment friendly, comprehensive yield is 52% more, than the existing 35.6% yield, with a remarkable enhancement, greatly reduces the production cost of the existing drugs, is suitable for industrial scale production. (by machine translation)

Process for the preparation of an intermediate for an orexin receptor antagonist

The present invention is directed to processes for preparing an intermediate for a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved.

PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST

The present invention is directed to processes for preparing a diazepane compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is further directed to crystalline forms of this diazepane compound and pharmaceutical compositions thereof.