127680-87-9 Usage
Uses
Used in Pharmaceutical Research:
2-Pyrrolidin-1-ylisonicotinonitrile is used as a research compound for its agonistic effects on the alpha-7 nicotinic acetylcholine receptor, which is implicated in cognitive and neurological disorders.
Used in Neurological and Cognitive Disorder Treatment:
2-Pyrrolidin-1-ylisonicotinonitrile is used as a potential therapeutic agent for treating conditions such as Alzheimer's disease, schizophrenia, and cognitive deficits due to its influence on the alpha-7 nicotinic acetylcholine receptor, which is believed to have a role in these conditions.
Used in Enhancing Memory and Cognitive Function:
In preclinical studies, 2-Pyrrolidin-1-ylisonicotinonitrile has demonstrated the ability to enhance memory and cognitive function, making it a candidate for further investigation in improving cognitive performance and treating related disorders.
Used in Drug Development for Neuroprotection:
Given its potential neuroprotective properties, 2-Pyrrolidin-1-ylisonicotinonitrile is being explored for its use in developing drugs that could protect neurons and potentially slow the progression of neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 127680-87-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,6,8 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127680-87:
(8*1)+(7*2)+(6*7)+(5*6)+(4*8)+(3*0)+(2*8)+(1*7)=149
149 % 10 = 9
So 127680-87-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H11N3/c11-8-9-3-4-12-10(7-9)13-5-1-2-6-13/h3-4,7H,1-2,5-6H2
127680-87-9Relevant academic research and scientific papers
A Study of the Photochemically Induced Electron-Transfer Reactions Between Pyridinedicarbonitriles and Primary and Secondary Aliphatic Amines
Bernardi, Rosanna,Caronna, Tullio,Poggi, Gabriella,Vittimberga, Bruno M.
, p. 903 - 908 (2007/10/02)
A study on the photochemically induced electron-transfer from primary and secondary aliphatic amines as donors to pyridinecarbonitriles as the acceptor is reported.A comparison between the substitution positions and the spin density distributions, obtained via teoretical calculations using the 6-31+G basis set, shows some discrepancies, and forms the basis of a hypothesis on the mechanism of the reaction.
A Study of the Photochemically Induced Reaction of Pyridine-2,4-dicarbonitrile with Primary and Secondary Amines. A Direct Synthesis of Aminocyanopyridines
Bernardi, Rosanna,Caronna, Tullio,Morrocchi, Sergio,Ursini, Maurizio,Vittimberga, Bruno M.
, p. 97 - 100 (2007/10/02)
A novel synthesis of alkylaminopyridinecarbonitriles by a photoinitiated substitution reaction between pyridine-2,4-dicarbonitrile and certain amines is described.The mechanism is discussed.
