127696-06-4

Upstream product

• 499-02-5 (1R,2R)-(+)-3-methylenecyclopropane-1,2-dicarboxylic acid 
• 138736-92-2 (2S,3R)-(+)-bis[hydroxymethyl]-1,1-dimethoxycyclobutane 
• 138736-91-1 (1S,2R)-3,3-Dimethoxy-cyclobutane-1,2-dicarboxylic acid bis-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 29737-65-3 dimethyl trans-3-methylenecyclopropane-1,2-dicarboxylate 
• 57637-10-2 (-)-trans-2(R),3(R)-bis(hydroxymethyl)methylenecyclopropane 
• 127759-87-9 (2S,3S)-3-methoxycarbonyl-1,1-bis(methylthio)-2-(2-oxo-oxazolidin-3-yl)carbonylcyclobutane 
• 127716-16-9 (-)-(2S,3S)-2,3-Bis(methoxycarbonyl)-1,1-bis(methylthio)-cyclobutane 
• 127759-88-0 (-)-(2S,3S)-2,3-bis(hydroxymethyl)-1,1-bis(methylthio)cyclobutane 
• 127696-05-3 (+)-(2S,3S)-2,3-bis(t-butyldiphenylsilyloxymethyl)-1,1-bis(methylthio)cyclobutane 
• 132164-71-7 C₃₈H₄₆O₂Si₂ 

Downstream Products

• 127696-07-5 (1S,2S,3S)-2,3-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-cyclobutanol 
• 127760-56-9 (1R,2S,3S)-2,3-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-cyclobutanol 

Relevant academic research and scientific papers

CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS

The present invention is directed to compounds of the formulae I, II and III as shown below wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

Method for epoxidation of 3-methylenecyclopropanes

The present invention provides a process for the expoxidation of a protected 3-methylene-(trans)-1,2,-hydroxymethylcyclopropane with cyclohexanone and potassium peroxymonosulfate and subsequent rearrangement to provide the corresponding cyclobutanone.

Efficient syntheses of protected (2s,3s)-2,3-bis(hydroxymethyl)cyclobutanone, key intermediates for the synthesis of chiral carbocyclic analogues of oxetanocin

Protected forms of (2S,3S)-2,3-bis(hydroxymethyl)cyclobutanone, key intermediates for the synthesis of chiral carbocyclic oxetanocin analogues, were prepared from Feist's acid.

Enantio- and Diastereo-selective Synthesis of Carbocyclic Oxetanocin Analogues

Carbocyclic oxetanocin-A (COXT-A) (2a) and -G (COTX-G) (2b) were synthesised enantio- and diastereo-selectively; these compounds exhibited potent antiviral activities.