127700-63-4

Basic information

• Product Name: (2S)-(N-para-toluenesulphonylamino)pentanoic acid tert-butyl ester
• Synonyms: (2S)-(N-para-toluenesulphonylamino)pentanoic acid tert-butyl ester
• CAS NO: 127700-63-4
• Molecular Weight: 327.445
• Mol File: 127700-63-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2S)-(N-para-toluenesulphonylamino)pentanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-(N-para-toluenesulphonylamino)pentanoic acid tert-butyl ester(127700-63-4)
• EPA Substance Registry System: (2S)-(N-para-toluenesulphonylamino)pentanoic acid tert-butyl ester(127700-63-4)

Safety Data

• Hazardous Substances Data: 127700-63-4(Hazardous Substances Data)

Upstream product

• 56-86-0 L-glutamic acid 
• 4816-80-2 N-tosyl-L-glutamic acid 
• 21957-65-3 1-(4'-methylbenzenesulfonyl)-5-oxopyrrolidine-2-carboxylic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 15911-75-8 (S)-2-aminopentanoic acid tert-butyl ester 
• 540-88-5 acetic acid tert-butyl ester 
• 2386-64-3 ethylmagnesium chloride 
• 127700-57-6 1-p-toluensulfonylaziridine-(2S)-carboxylic acid tert-butyl ester 

Downstream Products

• 6600-40-4 L-Norvaline 
• 1254719-17-9 (S)-tert-butyl 1-tosylpyrrolidine-2-carboxylate 
• 463962-06-3 tert-butyl (2S)-1-[(4-methylphenyl)sulfonyl]-2-pyrrolidinecarboxylate 
• 1269425-69-5 (2S)-tert-butyl 5-hydroxy-1-tosylpyrrolidine-2-carboxylate 

Relevant articles and documents

Overcoming the Deallylation Problem: Palladium(II)-Catalyzed Chemo-, Regio-, and Stereoselective Allylic Oxidation of Aryl Allyl Ether, Amine, and Amino Acids

We report herein a Pd(II)/bis-sulfoxide-catalyzed intramolecular allylic C-H acetoxylation of aryl allyl ether, amine, and amino acids with the retention of a labile allyl moiety. Mechanistically, the reaction proceeds through a distinct double-bond isomerization from the allylic to the vinylic position followed by intramolecular carboxypalladation and the β-hydride elimination pathway. For the first time, C-H oxidation of N-allyl-protected amino acids to furnish five-membered heterocycles through 1,3-syn-addition is established with excellent diastereoselectivity.

Amino Acid Synthesis via Ring Opening of N-Sulphonyl Aziridine-2-Carboxylate Esters with Organometallic Reagents.

Nucleophilic ring opening of optically active N-sulphonyl aziridine-2-carboxylate esters with organometallic reagents has been investigated as a method of preparation of optically active amino acids.Key Words: aziridine-2-carboxylate, cuprate, nucleophilic ring opening, amino acid