127717-34-4Relevant academic research and scientific papers
Acid-Catalyzed Reaction of Pyrazolopyridines with Aldehydes: Formation of Bis(pyrazolopyrid-3-yl)methanes
Miki, Yasuyoshi,Yagi, Sanae,Hachiken, Hiroko,Ikeda, Masazumi
, p. 1045 - 1046 (2007/10/02)
Reaction of pyrazolopyridines with aldehydes in the presence of trifluoroacetic acid gave bis(pyrazolopyrid-3-yl)methanes in high yields.
Acid-Catalyzed Reactions of 3-(Hydroxymethyl)- and 3-(1-Hydroxyethyl)pyrazolopyridines
Miki, Yasuyoshi,Nakamura, Noriko,Hachiken, Hiroko,Takemura, Shoji
, p. 1739 - 1745 (2007/10/02)
Treatment of 3-(hydroxymethyl)pyrazolopyridines with trifluoroacetic acid in refluxing dichloromethane led to the formation of bis(pyrazolopyrid-3-yl)methanes or bis pyrid-3-yl)>methyl ethers depending upon the concentration of trifluoroacetic acid.In contrast, similar treatment of 3-(1-hydroxyethyl)pyrazolopyridines gave a mixture of 3-vinylpyrazolopyridines and 1,3-bis(pyrazolopyrid-3-yl)-1-butenes.
