127717-17-3Relevant academic research and scientific papers
Unexpected cleavage of the Cpy-Cpybond in the reaction of 2,2′-bipyridine N,N′-diimines with acetylenes
Supranovich, Vyacheslav I.,Borodkin, Gennady I.,Vorob'Ev, Aleksey Yu.,Shubin, Vyacheslav G.
supporting information, p. 5377 - 5380 (2015/02/02)
An unusual cleavage of the Cpy-Cpybond in the reaction of 2,2′-bipyridine N,N′-diimine and its C-methyl substituted derivatives with acetylenes is described. The effect of the solvent on the yield of 7,7′-bipyrazolo[1,5-a]pyridine-2,2′,3,3′-tetracarboxylates and the products of cleavage of the Cpy-Cpybond has been studied. The mechanism of the cleavage reaction is discussed on the basis of DFT calculations.
PYRAZOLOPYRIDINE DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF
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Paragraph 0187; 0188, (2014/01/07)
A pyrazolopyridine derivative represented by the following formula (I) or a pharmacologically acceptable salt thereof exhibits a strong EP1 receptor antagonistic effect. Thus, the derivative or the pharmacologically acceptable salt is useful as
Acid-Catalyzed Reactions of 3-(Hydroxymethyl)- and 3-(1-Hydroxyethyl)pyrazolopyridines
Miki, Yasuyoshi,Nakamura, Noriko,Hachiken, Hiroko,Takemura, Shoji
, p. 1739 - 1745 (2007/10/02)
Treatment of 3-(hydroxymethyl)pyrazolopyridines with trifluoroacetic acid in refluxing dichloromethane led to the formation of bis(pyrazolopyrid-3-yl)methanes or bis pyrid-3-yl)>methyl ethers depending upon the concentration of trifluoroacetic acid.In contrast, similar treatment of 3-(1-hydroxyethyl)pyrazolopyridines gave a mixture of 3-vinylpyrazolopyridines and 1,3-bis(pyrazolopyrid-3-yl)-1-butenes.
