1277172-65-2

Upstream product

• 115586-67-9 (2R,3S)-3-O-benzyl-4-pentene-1,2,3-triol 
• 108275-52-1 (+)-(3S,4R)-3-benzyloxy-4,5-O-isopropylidene-4,5-dihydroxy-1-pentene 
• 100-39-0 benzyl bromide 
• 1277172-58-3 (2R,3S)-3-(benzyloxy)-1-(trityloxy)pent-4-en-2-ol 
• 1277172-63-0 (4S,5S,6S)-6-(benzyloxy)-5-(tert-butoxycarbonylamino)octa-1,7-dien-4-yl acetate 
• 1277172-62-9 tert-butyl (2R,3S)-[3-(benzyloxy)-1-oxopent-4-en-2-yl]carbamate 
• 1277172-61-8 tert-butyl (2S,3S)-[3-(benzyloxy)-1-(trityloxy)pent-4-en-2-yl]carbamate 
• 1277172-60-7 (2S,3S)-2-azido-3-(benzyloxy)-1-(trityloxy)pent-4-ene 
• 1277172-59-4 (2R,3S)-3-(benzyloxy)-1-(trityloxy)pent-4-en-2-yl methanesulfonate 
• 1042338-99-7 (1S,2S)-(2-benzyloxy-1-hydroxymethyl-but-3-enyl)-carbamic acid tert-butyl ester 

Downstream Products

• 1277172-66-3 (1R,2R,3R,4S,5S)-5-(acetoxy)-3-(benzyloxy)-4-(tert-butoxycarbonylamino)cyclohexane-1,2-diol 
• 1277172-67-4 (1R,2R,3R,4S,5S)-3-(benzyloxy)-4-(tert-butoxycarbonylamino)cyclohexane-1,2,5-triyl triacetate 
• 1279009-83-4 (1R,2R,3R,4S,5S)-4-aminocyclohexane-1,2,3,5-tetraol 

Relevant academic research and scientific papers

Synthesis of aminocyclitols and trihydroxylated indolizidinone from a D-mannitol-derived common building block

The synthesis of 4-amino-4-deoxy-muco-quercitol (22), 4-amino-4-deoxy-(-)- vibo-quercitol (27) and also a trihydroxylated indolizidinone 38 from D-mannitol is described using ring-closing metathesis and diastereoselective dihydroxylation as the key steps.