1277185-62-2

Upstream product

• 37142-87-3 4-methyl-1,4-benzothiazin-3(4H)-one 
• 137-07-5 2-amino-benzenethiol 
• 5325-20-2 2H-1,4-benzothiazin-3-one 
• 1277185-53-1 3-chloro-4-methyl-4H-benzo[b][1,4]thiazine 
• 99-92-3 p-aminobenzophenone 

Relevant academic research and scientific papers

Synthesis and antiinflammatory activity of some newer N-(substituted phenyl)-2HI4H-benzo [b] [1,4] thiazin-3-amines

2-Aminothiophenol on condensation with ethyl chloroacetate gave 2H-benzo [b] [1,4] thiazin-3[4H]-one 1 which on chlorination with POCl3 yielded 3- chloro-2H-benzo [b] [1,4]-thiazine 2, compound 2 with substituted anilines yielded N-(substituted phenyl)-2H-benzo [b] [1,4] thiazine-3-amines 3a-f. 2 on the other hand on methylation with methyl iodide gave 4-methyl-2H-benzo [b] [1,4] thiazin-3(4H)-one 4, which on chlorination with POCl3 yielded 3-chloro-4-methyl-4H-benzo [b] [1,4] thiazine 5,5 on treatment with substituted anilines gave 4-methyl-N-(substituted phenyl)-2H-benzo [b] [1,4]-thiazin-3-amines 6a-f. The structures of newly synthesized compounds were elucidated on the basis of FTIR, 1H NMR, mass and elemental analysis and screened for their antiinflammatory activity.