37142-87-3

Upstream product

• 79-08-3 bromoacetic acid 
• 21749-63-3 2-(methylamino)benzenethiol 
• 79-11-8 chloroacetic acid 
• 5325-20-2 2H-1,4-benzothiazin-3-one 
• 74-88-4 methyl iodide 
• 70413-84-2 4-methyl-4H-benzo[1,4]thiazin-3-ylideneamine; hydrochloride 
• 39639-85-5 4-methyl-4H-benzo[1,4]thiazine-3-thione 
• 105-36-2 ethyl bromoacetate 
• 67-64-1 acetone 
• 1239573-75-1 2-chloro-N-(2-iodophenyl)-N-methylacetamide 
• 137-07-5 2-amino-benzenethiol 
• 57056-93-6 N-methyl-2-iodoaniline 
• 1339628-12-4 N-(2-iodophenyl)-2-bromoacetamide 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 83170-55-2 2-benzyl-4-methyl-2H-benzo[b][1,4]thiazin-3(4H)-one 
• 55043-22-6 4-methyl-2-(4-methyl-benzylidene)-4H-benzo[1,4]thiazin-3-one 
• 55043-31-7 4-methyl-2-(3-phenyl-allylidene)-4H-benzo[1,4]thiazin-3-one 
• 55043-28-2 2-(2-fluoro-benzylidene)-4-methyl-4H-benzo[1,4]thiazin-3-one 
• 55043-29-3 4-methyl-2-(2-nitro-benzylidene)-4H-benzo[1,4]thiazin-3-one 
• 30752-17-1 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-one 
• 1277185-57-5 C₁₅H₁₃N₃O₂S 
• 1277185-58-6 C₁₅H₁₃BrN₂S 
• 1277185-59-7 C₁₅H₁₃ClN₂S 
• 1277185-60-0 C₁₅H₁₃FN₂S 
• 1277185-61-1 C₁₇H₁₆N₂OS 
• 1277185-62-2 C₁₇H₁₆N₂OS 
• 85809-67-2 (Z)-2-(4-chlorobenzylidene)-4-methyl-2H-benzo[b][1,4]thiazin-3(4H)-one 

Relevant academic research and scientific papers

An efficient ligand-free ferric chloride catalyzed synthesis of annulated 1,4-thiazine-3-one derivatives

A straight forward route for the synthesis of coumarin-, quinolone-annulated 1,4-thiazine-3-one derivatives has been achieved by using sodium sulfide as the sulfur source and ferric chloride as catalyst in a ligand-free condition. The synthetic procedure is simple, inexpensive, and affords the products in good yields. This methodology is also applicable to naphthalene and benzene systems.

An efficient ligand-free ferric chloride catalyzed synthesis of annulated 1,4-thiazine-3-one derivatives

A straight forward route for the synthesis of coumarin-, quinolone-annulated 1,4-thiazine-3-one derivatives has been achieved by using sodium sulfide as the sulfur source and ferric chloride as catalyst in a ligand-free condition. The synthetic procedure is simple, inexpensive, and affords the products in good yields. This methodology is also applicable to naphthalene and benzene systems.

Nickel-mediated inter- and intramolecular C-S coupling of thiols and thioacetates with aryl iodides at room temperature

A Ni(0)-catalyzed intermolecular cross-coupling of various functionalized thiols and aryl iodides has been developed and successfully extended to less explored intramolecular versions, where thioacetates could also be utilized as the strategic surrogate. Air-stable precatalysts, very mild conditions, and an easy protocol allow rapid access to medicinally useful aryl thioethers, as demonstrated in the facile synthesis of (±)-chuangxinmycin as a key step.

AZO METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM

To provide a dye to be used for an optical recording medium excellent in both high speed recording characteristics and reproduction durability. A dye having an azo compound represented by the following formula coordinated to a metal ion: wherein the ring

Synthesis and antiinflammatory activity of some newer N-(substituted phenyl)-2HI4H-benzo [b] [1,4] thiazin-3-amines

2-Aminothiophenol on condensation with ethyl chloroacetate gave 2H-benzo [b] [1,4] thiazin-3[4H]-one 1 which on chlorination with POCl3 yielded 3- chloro-2H-benzo [b] [1,4]-thiazine 2, compound 2 with substituted anilines yielded N-(substituted phenyl)-2H-benzo [b] [1,4] thiazine-3-amines 3a-f. 2 on the other hand on methylation with methyl iodide gave 4-methyl-2H-benzo [b] [1,4] thiazin-3(4H)-one 4, which on chlorination with POCl3 yielded 3-chloro-4-methyl-4H-benzo [b] [1,4] thiazine 5,5 on treatment with substituted anilines gave 4-methyl-N-(substituted phenyl)-2H-benzo [b] [1,4]-thiazin-3-amines 6a-f. The structures of newly synthesized compounds were elucidated on the basis of FTIR, 1H NMR, mass and elemental analysis and screened for their antiinflammatory activity.

Copper-catalyzed cascade syntheses of 2 H -benzo[ b ][1,4]thiazin-3(4 H)-ones and quinoxalin-2(1 H)-ones through capturing S and N atom respectively from AcSH and TsNH2

A copper-catalyzed cascade method has been developed to synthesize the 2H-benzo[b][1,4]thiazin-3(4H)-ones from 2-halo-N-(2-halophenyl)-acetamides 1 and AcSH via the SN2/deacetylation/coupling process, and to synthesize the quinoxalin-2(1H)-ones from 1 and TsNH2 via the S N2/coupling/desulfonation process. The target products were obtained with diversity at three positions on their scaffolds.

An alternative efficient method for transformation of thiocarbonyl to carbonyl group using trifluoroacetic anhydride

A simple and efficient procedure for the rapid and mild conversion of thiocarbonyls to carbonyls in high yields is described.

Synthesis, antibacterial and antifungal activities of several new benzo- naphtho- and quinolino-1,4-thiazine and 1,5-thiazepine derivatives

The synthesis of a number of thiosemicarbazone, phenylthiosemicarbazone, oxime and oxime O-ester derivatives of benzo- naphtho- and quinolino-1,4-thiazines and 1,5-thiazepines is described.All the compounds were tested in vitro for their antimicrobial act

An Improved Alkylation of 2H-1,4-Benzothiazin-3(4H)-one and Related Heterocyclic Anilides

Various N-substituted derivatives of 2H-1,4-benzothiazin-3(4H)-one are obtained in high yields employing functionalized alkyl halides and potassium tert-butoxide in dimethylformamide.The method is mild, regioselective and tolerates a variety of functional groups.