127792-84-1 Usage
Chemical compound
1,2-BIS(METHYLSULFONYL)-1-(2-CHLOROETHYL)HYDRAZINE is a chemical compound used in the development of cancer drugs.
Class of agents
It belongs to the class of alkylating agents, which work by attaching an alkyl group to DNA.
Mechanism of action
The alkyl group causes damage to the DNA strands, preventing cancer cells from dividing and growing.
Preclinical studies
1,2-BIS(METHYLSULFONYL)-1-(2-CHLOROETHYL)HYDRAZINE has shown promising results in preclinical studies for the treatment of various types of cancer, including lung, breast, and prostate cancer.
Potential efficacy
Its mechanism of action and potential efficacy make it a valuable candidate for further research and development as a cancer treatment.
Safety and effectiveness
More research is needed to fully understand its safety and effectiveness in clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 127792-84-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,9 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 127792-84:
(8*1)+(7*2)+(6*7)+(5*7)+(4*9)+(3*2)+(2*8)+(1*4)=161
161 % 10 = 1
So 127792-84-1 is a valid CAS Registry Number.
127792-84-1Relevant academic research and scientific papers
Process for the synthesis of anti-neoplasia agent VNP40101M
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Page/Page column 5, (2011/10/12)
The present invention relates to simple, safe, high-yield methods of synthesizing VNP40101M, 1,2-bis(methylsulfonyl)-2-(2-chloroethyl)-2-(methylaminocarbonyl)hydrazine, an anti-neoplasia agent. One particularly preferred method uses methyl chloroformamide in a one-pot reaction at elevated temperatures to provide VNP40101M in high yield.
Synthesis and evaluation of 1,2,2-tris(sulfonyl)hydrazines as antineoplastic and trypanocidal agents
Shyam,Penketh,Divo,Loomis,Patton,Sartorelli
, p. 2259 - 2264 (2007/10/02)
Several 1,2,2-tris(sulfonyl)hydrazines, conceived as prodrugs of 1,2-bis(sulfonyl)hydrazines, were synthesized and evaluated for antineoplastic and trypanocidal activities in mice. 1-Methyl-1,2,2-tris(methylsulfonyl)hydrazine emerged as an extremely effic
