127793-03-7 Usage
Type of Compound
Hydrazine derivative
Functional Groups
Contains two methylsulfonyl groups and an oxyethyl bridge
Usage
a. Solvent for various applications
b. Precursor for the synthesis of other organic compounds
Industry Applications
a. Pharmaceutical industry for drug development
b. Production of polymers
c. Reagent in chemical reactions
Potential Properties
a. Anti-inflammatory
b. Anti-cancer
Research Interest
Subject of interest for further research in the field of medicinal chemistry
Check Digit Verification of cas no
The CAS Registry Mumber 127793-03-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,9 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127793-03:
(8*1)+(7*2)+(6*7)+(5*7)+(4*9)+(3*3)+(2*0)+(1*3)=147
147 % 10 = 7
So 127793-03-7 is a valid CAS Registry Number.
127793-03-7Relevant academic research and scientific papers
Process for the synthesis of anti-neoplasia agent VNP40101M
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Page/Page column 4-5, (2011/10/12)
The present invention relates to simple, safe, high-yield methods of synthesizing VNP40101M, 1,2-bis(methylsulfonyl)-2-(2-chloroethyl)-2-(methylaminocarbonyl)hydrazine, an anti-neoplasia agent. One particularly preferred method uses methyl chloroformamide in a one-pot reaction at elevated temperatures to provide VNP40101M in high yield.
Synthesis and evaluation of 1,2,2-tris(sulfonyl)hydrazines as antineoplastic and trypanocidal agents
Shyam,Penketh,Divo,Loomis,Patton,Sartorelli
, p. 2259 - 2264 (2007/10/02)
Several 1,2,2-tris(sulfonyl)hydrazines, conceived as prodrugs of 1,2-bis(sulfonyl)hydrazines, were synthesized and evaluated for antineoplastic and trypanocidal activities in mice. 1-Methyl-1,2,2-tris(methylsulfonyl)hydrazine emerged as an extremely effic