127844-72-8

Upstream product

• 130820-59-6 (E)-1-(2-aminophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 551-93-9 2-aminoacetophenone 
• 127844-65-9 N-{2-[2-Bromo-3-methoxy-3-(4-methoxy-phenyl)-propionyl]-phenyl}-benzenesulfonamide 
• 127844-63-7 N-{2-[2,3-Dibromo-3-(4-methoxy-phenyl)-propionyl]-phenyl}-benzenesulfonamide 

Downstream Products

• 136490-97-6 erythro-2-hydroxy-3-methoxy-1-(2'-aminophenyl)-3-(4-methoxyphenyl)-propan-1-one 
• 136491-00-4 threo-1-(2'-aminobenzoyl)-2-(4-methylphenyl)-ethylene chlorohydrin 
• 127844-73-9 Acetic acid 3-(2-amino-phenyl)-2-hydroxy-1-(4-methoxy-phenyl)-3-oxo-propyl ester 

Relevant academic research and scientific papers

Intramolecular aminolysis of 2-aminochalcone epoxides using InBr 3 or BiCl3 as efficient catalysts

In the synthesis of aza-flavanone derivatives, several metal halides were screened for their catalytic activity. Among them, BiCl3 and InBr3 catalyze the ring opening of 2-aminochalcone epoxides followed by intramolecular aminolysis

Chalcone derivatives as precursors of 1,2,3,4-tetrahydro-4-quinolones

2-Aryl-1,2,3,4-tetrahydro-4-quinolones were synthesised from 2′-amino-4-methoxychalcone and its 2′-benzenesulphonamido derivative by acid and base catalysis, respectively. The α,β-dibromo and α-bromo-β-methoxy derivatives of 2′-benzenesulphonamido-4-methoxydihydrochalcone cyclised to 2-aryl-3-bromo-1,2,3,4-tefrahydro-4-quinolones as did the corresponding α-bromochalcones. 2′-Amino-4-methoxychalcone formed a stable epoxide.