1278509-69-5

Basic information

• Product Name: Cys-Phe-Arg-Ala-Asn-Lys-OH
• CAS NO: 1278509-69-5
• Molecular Weight: 737.881
• Mol File: 1278509-69-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cys-Phe-Arg-Ala-Asn-Lys-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Cys-Phe-Arg-Ala-Asn-Lys-OH(1278509-69-5)
• EPA Substance Registry System: Cys-Phe-Arg-Ala-Asn-Lys-OH(1278509-69-5)

Safety Data

• Hazardous Substances Data: 1278509-69-5(Hazardous Substances Data)

Upstream product

• 15761-38-3 L-N-Boc-Ala 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 13836-37-8 Boc-Arg(Tos)-OH 
• 54613-99-9 Boc-(S)-Lys(2-Cl-Z)-OH 
• 65420-40-8 (S)-2-tert-Butoxycarbonylamino-N-(9H-xanthen-9-yl)-succinamic acid 
• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 35661-40-6 N-Fmoc L-Phe 
• 132388-59-1 L-Asn(Trt) 
• 67436-13-9 (R)-3-tert-Butylsulfanyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid 

Downstream Products

• 1356006-89-7 LYRAPCFRANK 
• 1356006-91-1 LYRAFCFRANK 

Relevant articles and documents

Bis(2-sulfanylethyl)amido peptides enable native chemical ligation at proline and minimize deletion side-product formation

Native chemical ligation of C-terminal peptidyl prolyl alkylthioesters with N-terminal cysteinyl peptides usually exhibits poor kinetic rates compared to other C-terminal amino acid residues. It is shown here that the reaction is accompanied by the formation of a deletion side product which is minimized by using a bis(2-sulfanylethyl)amido (SEA) thioester surrogate at a mildly acidic pH.