1279038-40-2

Upstream product

• 736131-48-9 (S)-3-amino-3-(2-methylphenyl)propionic acid 
• 1239726-11-4 1-(2-fluoro-phenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 1318790-02-1 1-(2-fluoro-phenyl)-5-methoxy-1H-pyrazole-3-carbonyl chloride 
• 1318789-59-1 1-(2-fluorophenyl)-5-hydroxy-1H-pyrazole-3-carboxylic acid 
• 1318789-62-6 ethyl (S)-3-amino-3-(2-methyl-phenyl)-propionate hydrochloride 
• 1318789-61-5 1-(2-fluorophenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid methyl ester 
• 1246555-84-9 methyl 1-(2-fluorophenyl)-5-hydroxy-1H-pyrazole-3-carboxylate 
• 2924-15-4 (2-fluorophenyl)hydrazine hydrochloride 

Downstream Products

• 1318789-20-6 1-(2-fluoro-phenyl)-5-methoxy-1H-pyrazole-3-carboxylic acid [(S)-2-(1,1-dimethyl-propylcarbamoyl)-1-o-tolyl-ethyl]-amide 
• 1279032-89-1 (S)-3-{[1-(2-fluoro-phenyl)-5-methoxy-1H-pyrazole-3-carbonyl]-amino}-3-(2-methyl-phenyl)-propionic acid amide 

Relevant academic research and scientific papers

Novel β-amino acid derivatives as inhibitors of cathepsin A

Cathepsin A (CatA) is a serine carboxypeptidase distributed between lysosomes, cell membrane, and extracellular space. Several peptide hormones including bradykinin and angiotensin I have been described as substrates. Therefore, the inhibition of CatA has

OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

The present invention relates to compounds of the formula I, wherein A, D, E, G, R10, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable pharmaceutical active compound