127942-30-7

Basic information

• Product Name: ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE
• Synonyms: 4-THIAZOLECARBOXYLIC ACID, 2-AMINO-, ETHYL ESTER;AKOS BBV-000509;ETHYL-2-AMINOTHIAZOLE-4-CARBOXYLIC ACID;2-Aminothiazole-4-carboxylic acid ethyl ester hydrobromide;2-Aminothiazole-4-carboxylic acid ethyl ester monohydrobromide;ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE hcl;ethyl 2-aMinothiazol-4-carboxylate HBr;2-Amino-4-(ethoxycarbonyl)-1,3-thiazole hydrobromide
• CAS NO: 127942-30-7
• Molecular Formula: C6H8N2O2S
• Molecular Weight: 0
• Mol File: 127942-30-7.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE(127942-30-7)
• EPA Substance Registry System: ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE(127942-30-7)

Safety Data

• Hazardous Substances Data: 127942-30-7(Hazardous Substances Data)

Usage

General Description

ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE is a chemical compound that consists of a thiazole ring with an amino group and a carboxylate group attached to it. It is commonly used in the synthesis of pharmaceuticals and agrochemicals, serving as a building block for the production of various bioactive molecules. ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE has also been studied for its potential biological activities, including antimicrobial, antifungal, and anti-inflammatory properties. Additionally, it has been investigated for its potential use in the development of new materials and catalysts. Overall, ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE is a versatile compound with various applications in the fields of chemistry, medicine, and materials science.

Upstream product

• 70-23-5 ethyl Bromopyruvate 
• 62-56-6 thiourea 
• 1378831-76-5 ethyl bromopyruvate 
• 17356-08-0 thiourea 

Downstream Products

• 232596-68-8 ethyl 2-phenoxycarbonyl-amino-thiazole-4-carboxylate 

Relevant articles and documents

Soluble head-to-tail regioregular polythiazoles: Preparation, properties, and evidence for chain-growth behavior in the synthesis via Kumada-Coupling polycondensation

Head-to-tail regioregular poly(4-alkylthiazole)s containing silylethers in the side-chains were synthesized via Kumada-Coupling polycondensation of "reversed" monomers, that were metalated at the sterically hindered 5-position. Their optical, electrochemi

Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema

Vascular adhesion protein-1 (VAP-1), an amine oxidase that is also known as a semicarbazide-sensitive amine oxidase (SSAO), is present in particularly high levels in human plasma, and is considered a potential therapeutic target for various inflammatory diseases, including diabetes complications such as macular edema. In our VAP-1 inhibitor program, structural modifications following high-throughput screening (HTS) of our compound library resulted in the discovery that thiazole derivative 10, which includes a guanidine group, shows potent human VAP-1 inhibitory activity (IC50 of 230 nM; rat IC 50 of 14 nM). Moreover, compound 10 exhibited significant inhibitory effects on ocular permeability in STZ-induced diabetic rats.

EP2 RECEPTOR AGONISTS

A compound of Formula (I) or a salt, solvate and chemically protected form thereof, wherein: R5 is an optionally substituted C5-20 aryl or C4-20 alkyl group; A is selected from the group consisting of Formulae (Ai), (Aii), (Aiii) D is selected from Formulae (Di), (Dii), (Diii), (Div), (Dv) B is selected from the group consisting of Formulae (Bi), (Bii), (Biii), (Biv) (Bv).