127953-31-5

Basic information

• Product Name: 2-[(S)-2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonic acid benzyl ester methyl ester
• Synonyms: 2-[(S)-2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonic acid benzyl ester methyl ester
• CAS NO: 127953-31-5
• Molecular Weight: 519.576
• Mol File: 127953-31-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(S)-2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonic acid benzyl ester methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(S)-2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonic acid benzyl ester methyl ester(127953-31-5)
• EPA Substance Registry System: 2-[(S)-2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonic acid benzyl ester methyl ester(127953-31-5)

Safety Data

• Hazardous Substances Data: 127953-31-5(Hazardous Substances Data)

Upstream product

• 124278-39-3 N-(4-MorpholinYlsulfonyl)-L-phenylalanine 
• 127953-30-4 benzyl methyl aminomalonate hydrochloride 
• 52267-39-7 benzyl methyl malonate 
• 118283-56-0 2-[(Z)-Hydroxyimino]-malonic acid benzyl ester methyl ester 

Downstream Products

• 131176-63-1 N-(4-morpholinylsulfonyl)-L-phenylalanyl-DL-2-(methoxycarbonyl)glycine methyl ester 
• 127953-25-7 <1S-(1R^*,2S^*,3R^*)>-3-<<1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl>amino>-N--3-oxo-DL-alanine 
• 127953-03-1 PD 132002 
• 127953-07-5 <1S-(1R^*,2S^*,3R^*)>-3-<<1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl>amino>-N--3-oxo-DL-alanine isopropyl ester 
• 134335-02-7 <1S-(1R^*,2S^*,3R^*)>-3-<<1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl>amino>-N--3-oxo-DL-alanine n-hexyl ester 
• 134335-01-6 <1S-(1R^*,2S^*,3R^*)>-3-<<1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl>amino>-N--3-oxo-DL-alanine allyl ester 
• 124278-48-4 *,R^*)>-N--3-<<2-hydroxy-1-(2-methylpropyl)-4-<<2-(4-morpholinyl)ethyl>amino>-4-oxobutyl>amino>-3-oxo-DL-alanine methyl ester 
• 124278-25-7 *,R^*)>-3-<<1-(cyclohexylmethyl)-2-hydroxy-4<<2-(4-morpholinyl)ethyl>amino>-4-oxobutyl>amino>-N--3-oxo-DL-alanine methyl ester 
• 134334-93-3 3-<<1(S)-(cyclohexylmethyl)-3,3-difluoro-2(R)-hydoxy-4-<<2-(4-morpholinyl)ethyl>amino>-4-oxobutyl>amino>-N--3-oxo-DL-alanine methyl ester 
• 134334-94-4 (S)-3-<<1-(cyclohexylmethyl)-3,3-difluoro-4-<<2-(4-morpholino)ethyl>amino>-2,4-dioxobutyl>amino>-N--3-oxo-DL-alanine methyl ester methanesulfonate 

Relevant articles and documents

Renin Inhibitors Containing Esters at the P2-Position. Oral Activity in a Derivative of Methyl Aminomalonate

A series of renin inhibitors containing ester side chains at the P2 subsite are potent inhibitors of primate renin.Derivatives containing the diol isostere (ACDMH) at P1-P'1 were the most potent inhibitors.Moderate selectivity for re