127970-42-7

Basic information

• Product Name: Cytidine, 2'-deoxy-, 3',5'-bis(4-chlorobenzoate)
• CAS NO: 127970-42-7
• Molecular Formula: C23H19Cl2N3O6
• Molecular Weight: 504.326
• Mol File: 127970-42-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cytidine, 2'-deoxy-, 3',5'-bis(4-chlorobenzoate)(CAS DataBase Reference)
• NIST Chemistry Reference: Cytidine, 2'-deoxy-, 3',5'-bis(4-chlorobenzoate)(127970-42-7)
• EPA Substance Registry System: Cytidine, 2'-deoxy-, 3',5'-bis(4-chlorobenzoate)(127970-42-7)

Safety Data

• Hazardous Substances Data: 127970-42-7(Hazardous Substances Data)

Upstream product

• 71-30-7 Cytosine 
• 21740-23-8 3,5-O-bis(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 5173-91-1 3',5'-O-bis(4-chlorobenzoyl)-2'-deoxy-β-D-uridine 

Downstream Products

• 3992-42-5 2'-deoxycytidine monohydrochloride 

Relevant articles and documents

Method for producing nucleosides by direct glycosylation of the nucleoside base

Summary Method of producing a free nucleoside compound by reacting a a glycoside donor preferably a 1-halogen derivative, or 1-0-acyl, 1-o-alkyl, or an imidate preferably a trichloromethyl derivative, or a thio-alkyl derivative of a blocked monosaccharide or oligosaccharide preferably ribose and 2-desoxyribose derivatives with a protected nucleoside base, in a suitable anhydrous solvent and in the presence of a catalyst, and removing the protecting groups from said blocked nucleoside compound, wherein said catalyst is selected from the group comprising salts of an aliphatic sulphonic acid and/or salts of a optionally substituted aromatic sulphonic acid.

Process for the preparation of cytidine derivatives

An efficient method for producing cytidine derivatives that took away the previous drawbacks by efficiently synthesizing cytidine derivatives by utilizing a tertiary amine can be provided.