1279703-95-5Relevant articles and documents
Organocatalytic synthesis of spiro compounds via a cascade Michael-Michael-aldol reaction
Companyo, Xavier,Zea, Alex,Alba, Andrea-Nekane R.,Mazzanti, Andrea,Moyano, Albert,Rios, Ramon
, p. 6953 - 6955 (2010)
The synthesis of spiro compounds via a Michael-Michael-aldol reaction is reported. The reaction affords spirooxindole derivatives in good yields and in almost diastereo- and enantiopure form. Moreover, the reaction works with several heterocycles such as oxindoles, benzofuranones, pyrazolones or azlactones rendering the final spiro compounds in good yields and excellent stereoselectivities.
Highly stereoselective synthesis of spiropyrazolones
Alba, Andrea-Nekane R.,Zea, Alex,Valero, Guillem,Calbet, Teresa,Font-Bardia, Merce,Mazzanti, Andrea,Moyano, Albert,Rios, Ramon
experimental part, p. 1318 - 1325 (2011/04/17)
The synthesis of spiro compounds through a Michael-Michael-aldol reaction is reported. The reaction affords spiropyrazolone derivatives in good yields, in almost diastereo- and enantiopure form, and is catalyzed by diphenylprolinol derivatives. The reacti